Tuberculosis (TB) was announced as a global emergency in 1993. There was an alarming
counter attack of TB worldwide. However, when it was known that TB can be cured …

Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and
control programmes worldwide. Advances in sequencing technology have significantly …

Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by
the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …

Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are generally
thought to have high mortality rates. However, many cases can be treated with the right …

Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared
as a global emergency in 1993 by the WHO, its control is hampered by the emergence of …

Drug resistance in tuberculosis (TB) is a particular problem because the lengthy therapy of
at least 6 months makes patient compliance very difficult, which frequently creates drug …

Tuberculosis is today amongst the worldwide health threats. As resistant strains of
Mycobacterium tuberculosis have slowly emerged, treatment failure is too often a fact …

Fluoroquinolone resistance in Mycobacterium tuberculosis has become increasingly
important. A review of mutations in DNA gyrase, the fluoroquinolone target, is needed to …

Infectious diseases caused by clinically important Mycobacteria continue to be an important
public health problem worldwide primarily due to emergence of drug resistance crisis. In …

Two mechanisms are thought to be involved in the natural drug resistance of mycobacteria:
the mycobacterial cell wall permeability barrier and active multidrug efflux pumps. Genes …