Omics approaches are high-throughput unbiased technologies that provide snapshots of
various aspects of biological systems and include: 1) genomics, the measure of DNA …

Chronic obstructive pulmonary disease (COPD) patients frequently suffer from multiple
comorbidities, resulting in poor outcomes for these patients. Diabetes is observed at a …

Rationale: Chronic obstructive pulmonary disease (COPD) is variable in its development.
Lung microbiota and metabolites collectively may impact COPD pathophysiology, but …

Background: Pulmonary arterial hypertension (PAH) is a heterogeneous disorder with high
mortality. Methods: We conducted a comprehensive study of plasma metabolites using …

Lung macrophage subpopulations have been identified based on size. We investigated
characteristics of small and large macrophages in the alveolar spaces and lung interstitium …

Circulating endothelial microparticles (EMPs) are emerging as biomarkers of chronic
obstructive pulmonary disease (COPD) in individuals exposed to cigarette smoke (CS), but …

Dysregulated lipid metabolism plays crucial roles in various diseases, including diabetes
mellitus, cancer, and neurodegeneration. Recent studies suggest that alterations in major …

Dietary fiber functions as a prebiotic to determine the gut microbe composition. The gut
microbiota influences the metabolic functions and immune responses in human health. The …

Sphingolipid bioactivities in the respiratory airways and the roles of the proteins that handle
them have been extensively investigated. Gas or inhaled particles or microorganisms come …

Bronchiectasis is a complex and heterogeneous inflammatory chronic respiratory disease
with an unknown cause in around 30–40% of patients. The presence of airway infection …