Fructose and hepatic insulin resistance

S Softic, KL Stanhope, J Boucher… - Critical reviews in …, 2020 - Taylor & Francis
Excessive caloric intake in a form of high-fat diet (HFD) was long thought to be the major risk
factor for development of obesity and its complications, such as fatty liver disease and …

Mesenchymal stem cell exosomes as a new strategy for the treatment of diabetes complications

J Xiong, H Hu, R Guo, H Wang, H Jiang - Frontiers in Endocrinology, 2021 - frontiersin.org
Diabetes mellitus (DM) is a metabolic disease, now prevalent worldwide, which is
characterized by a relative or absolute lack of insulin secretion leading to chronically …

Profiling of serum exosome MiRNA reveals the potential of a MiRNA panel as diagnostic biomarker for Alzheimer's disease

Z Dong, H Gu, Q Guo, S Liang, J Xue, F Yao, X Liu… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease in the older
adults. Although much effort has been made in the analyses of diagnostic biomarkers, such …

miR-582-3p and miR-582-5p suppress prostate cancer metastasis to bone by repressing TGF-β signaling

S Huang, C Zou, Y Tang, Q Wa, X Peng, X Chen… - … Therapy-Nucleic Acids, 2019 - cell.com
A number of studies have reported that aberrant expression of microRNAs (miRNAs) closely
correlates with the bone metastasis of prostate cancer (PCa). However, clinical significance …

Fructose-mediated effects on gene expression and epigenetic mechanisms associated with NAFLD pathogenesis

JK DiStefano - Cellular and Molecular Life Sciences, 2020 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a chronic, frequently progressive condition that
develops in response to excessive hepatocyte fat accumulation (ie, steatosis) in the absence …

Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients

D Ye, T Zhang, G Lou, W Xu, F Dong, G Chen, Y Liu - Life sciences, 2018 - Elsevier
Aims Type 2 diabetes mellitus (T2DM), with non-alcoholic fatty liver disease (NAFLD)
complication, may aggravate the disturbance of metabolism, increase the risk of non …

High fructose intake and adipogenesis

A Hernández-Díazcouder, R Romero-Nava… - International journal of …, 2019 - mdpi.com
In modern societies, high fructose intake from sugar-sweetened beverages has contributed
to obesity development. In the diet, sucrose and high fructose corn syrup are the main …

High fructose diet-induced metabolic syndrome: pathophysiological mechanism and treatment by traditional Chinese medicine

Y Pan, LD Kong - Pharmacological research, 2018 - Elsevier
Fructose is a natural monosaccharide broadly used in modern society. Over the past few
decades, epidemiological studies have demonstrated that high fructose intake is an …

miR-128-3p inhibits intramuscular adipocytes differentiation in chickens by downregulating FDPS

S Zhu, B Zhang, T Zhu, D Wang, C Liu, Y Liu, Y He… - BMC genomics, 2023 - Springer
Background Intramuscular fat (IMF) content is the major indicator for evaluating chicken
meat quality due to its positive correlation with tenderness, juiciness, and flavor. An …

A new insight into the roles of MiRNAs in metabolic syndrome

Y Huang, Y Yan, W Xv, G Qian, C Li… - BioMed research …, 2018 - Wiley Online Library
Metabolic syndrome (MetS), which includes several clinical components such as abdominal
obesity, insulin resistance (IR), dyslipidemia, microalbuminuria, hypertension …