Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence
BACKGROUND Within the antral follicle, the oocyte is reliant on metabolic support from its
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …
Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events
M Conti, F Franciosi - Human reproduction update, 2018 - academic.oup.com
Infertility affects~ 7% of couples of reproductive age with little change in incidence in the last
two decades. ART, as well as other interventions, have made major strides in correcting this …
two decades. ART, as well as other interventions, have made major strides in correcting this …
The epidermal growth factor network: role in oocyte growth, maturation and developmental competence
D Richani, RB Gilchrist - Human reproduction update, 2018 - academic.oup.com
BACKGROUND The LH surge induces great physiological changes within the preovulatory
follicle, which culminate in the ovulation of a mature oocyte that is capable of supporting …
follicle, which culminate in the ovulation of a mature oocyte that is capable of supporting …
Oocyte maturation and quality: role of cyclic nucleotides
The developing fetus requires substantial amounts of fatty acids to support rapid cellular
growth and activity. Although the fatty acid composition delivered to the fetus is largely …
growth and activity. Although the fatty acid composition delivered to the fetus is largely …
An improved IVM method for cumulus-oocyte complexes from small follicles in polycystic ovary syndrome patients enhances oocyte competence and embryo yield
STUDY QUESTION Are meiotic and developmental competence of human oocytes from
small (2–8 mm) antral follicles improved by applying an optimized IVM method involving a …
small (2–8 mm) antral follicles improved by applying an optimized IVM method involving a …
Cytokines in ovarian folliculogenesis, oocyte maturation and luteinisation
SL Field, T Dasgupta, M Cummings… - Molecular reproduction …, 2014 - Wiley Online Library
Cytokines are key regulators of ovarian physiology, particularly in relation to folliculogenesis
and ovulation, where they contribute to creating an environment supporting follicle selection …
and ovulation, where they contribute to creating an environment supporting follicle selection …
Cumulin, an oocyte-secreted heterodimer of the transforming growth factor-β family, is a potent activator of granulosa cells and improves oocyte quality
Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are
oocyte-specific growth factors with central roles in mammalian reproduction, regulating …
oocyte-specific growth factors with central roles in mammalian reproduction, regulating …
Epigenetic dynamics during preimplantation development
In vitro maturation (IVM) offers significant benefits for human infertility treatment and animal
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes
J Chen, S Torcia, F Xie, CJ Lin, H Cakmak… - Nature cell …, 2013 - nature.com
Germ cells divide and differentiate in a unique local microenvironment under the control of
somatic cells. Signals released in this niche instruct oocyte reentry into the meiotic cell cycle …
somatic cells. Signals released in this niche instruct oocyte reentry into the meiotic cell cycle …
[HTML][HTML] Oocyte in vitro maturation: physiological basis and application to clinical practice
RB Gilchrist, J Smitz - Fertility and sterility, 2023 - Elsevier
Oocyte in vitro maturation (IVM) is an assisted reproductive technology with a long and
sometimes checked history. It is a minimally invasive technique involving the deliberate …
sometimes checked history. It is a minimally invasive technique involving the deliberate …