The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

Eukaryotic genomes are prevalently transcribed into many types of RNAs that translate into
proteins or execute gene regulatory functions. Many RNAs associate with chromatin directly …

Background Prostate cancer (PCa) is the most common malignant cancer in western
developed countries, which has seriously threatened the life style and life quality of men. Its …

Long non‐coding RNAs (lncRNAs) have come out as critical molecular regulators of human
tumorigenesis. In this study, we sought to identify and functionally characterize lncRNAs as …

Background Therapy for patients with liver cancer in the advanced stage remains a great
challenge, and there are very few approved treatments. Although accumulated evidence …

For several decades, research in tumor biology has focused on the involvement of genes
encoding a protein. Only recently has it been discovered that a whole class of molecules …

Angiogenesis has an important role in tumour cell growth and metastasis. Anisomycin has
been shown to inhibit tumour cell growth. However, whether anisomycin can inhibit …

Despite an ever-increasing appreciation of how protein-coding genes shape immune
responses, the molecular underpinnings of immune regulation remain incompletely …

Colorectal cancer (CRC) is one of the most common gastrointestinal cancers, with extremely
high rates of morbidity and mortality. The main cause of death in CRC is distant metastasis; it …

Epilepsy represents one of the most common neurological disorders characterized by
abnormal electrical activity in the central nervous system (CNS). Recurrent seizures are the …