Hepatitis C virus infection
MP Manns, M Buti, ED Gane, JM Pawlotsky… - Nature reviews Disease …, 2017 - nature.com
Hepatitis C virus (HCV) is a hepatotropic RNA virus that causes progressive liver damage,
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
TKH Scheel, CM Rice - Nature medicine, 2013 - nature.com
More than two decades of intense research has provided a detailed understanding of
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …
[PDF][PDF] Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource
The 2005 consensus proposal for the classification of hepatitis C virus (HCV) presented an
agreed and uniform nomenclature for HCV variants and the criteria for their assignment into …
agreed and uniform nomenclature for HCV variants and the criteria for their assignment into …
Detection of zoonotic pathogens and characterization of novel viruses carried by commensal Rattus norvegicus in New York City
Norway rats (Rattus norvegicus) are globally distributed and concentrate in urban
environments, where they live and feed in closer proximity to human populations than most …
environments, where they live and feed in closer proximity to human populations than most …
Virome capture sequencing enables sensitive viral diagnosis and comprehensive virome analysis
Insensitivity and technical complexity have impeded the implementation of high-throughput
nucleic acid sequencing in differential diagnosis of viral infections in clinical laboratories …
nucleic acid sequencing in differential diagnosis of viral infections in clinical laboratories …
[HTML][HTML] Virology and cell biology of the hepatitis C virus life cycle–An update
J Dubuisson, FL Cosset - Journal of hepatology, 2014 - Elsevier
Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
Hepatitis C virus E2 envelope glycoprotein core structure
Hepatitis C virus (HCV), a Hepacivirus, is a major cause of viral hepatitis, liver cirrhosis, and
hepatocellular carcinoma. HCV envelope glycoproteins E1 and E2 mediate fusion and entry …
hepatocellular carcinoma. HCV envelope glycoproteins E1 and E2 mediate fusion and entry …
Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family
Proposals are described for the assignment of recently reported viruses, infecting rodents,
bats and other mammalian species, to new species within the Hepacivirus and Pegivirus …
bats and other mammalian species, to new species within the Hepacivirus and Pegivirus …
[HTML][HTML] Viral pathogen discovery
CY Chiu - Current opinion in microbiology, 2013 - Elsevier
Highlights•Pathogen discovery is critically important to infectious diseases and public
health.•Nearly all new outbreaks are caused by the emergence of novel viruses.•Genomic …
health.•Nearly all new outbreaks are caused by the emergence of novel viruses.•Genomic …
Analyses of evolutionary dynamics in viruses are hindered by a time-dependent bias in rate estimates
Time-scales of viral evolution and emergence have been studied widely, but are often poorly
understood. Molecular analyses of viral evolutionary time-scales generally rely on estimates …
understood. Molecular analyses of viral evolutionary time-scales generally rely on estimates …