Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
Spontaneous preterm birth: advances toward the discovery of genetic predisposition
Evidence from family and twin-based studies provide strong support for a significant
contribution of maternal and fetal genetics to the timing of parturition and spontaneous …
contribution of maternal and fetal genetics to the timing of parturition and spontaneous …
Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
Inflammasomes: their role in normal and complicated pregnancies
Inflammasomes are cytoplasmic multiprotein complexes that coordinate inflammatory
responses, including those that take place during pregnancy. Inflammasomes and their …
responses, including those that take place during pregnancy. Inflammasomes and their …
Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes
EH Dutta, F Behnia, I Boldogh… - MHR: Basic science …, 2016 - academic.oup.com
STUDY HYPOTHESIS In women with preterm premature rupture of the membranes
(PPROM), increased oxidative stress may accelerate premature cellular senescence …
(PPROM), increased oxidative stress may accelerate premature cellular senescence …
Evidence of perturbations of the cytokine network in preterm labor
Objective Intraamniotic inflammation/infection is the only mechanism of disease with
persuasive evidence of causality for spontaneous preterm labor/delivery. Previous studies …
persuasive evidence of causality for spontaneous preterm labor/delivery. Previous studies …
A rapid interleukin-6 bedside test for the identification of intra-amniotic inflammation in preterm labor with intact membranes
P Chaemsaithong, R Romero… - The Journal of …, 2016 - Taylor & Francis
Objective: Preterm birth is associated with 5–18% of pregnancies and is the leading cause
of neonatal morbidity and mortality. Amniotic fluid (AF) interleukin-6 (IL-6) is a key cytokine …
of neonatal morbidity and mortality. Amniotic fluid (AF) interleukin-6 (IL-6) is a key cytokine …
Intra-amniotic inflammation induces preterm birth by activating the NLRP3 inflammasome
J Faro, R Romero, G Schwenkel… - Biology of …, 2019 - academic.oup.com
Intra-amniotic inflammation is strongly associated with spontaneous preterm labor and birth,
the leading cause of perinatal mortality and morbidity worldwide. Previous studies have …
the leading cause of perinatal mortality and morbidity worldwide. Previous studies have …
Ureaplasma species and preterm birth: current perspectives
KE Sprong, M Mabenge, CA Wright… - Critical reviews in …, 2020 - Taylor & Francis
Preterm birth is the leading cause of neonatal morbidity and mortality worldwide, and the
human Ureaplasma species are most frequently isolated from the amniotic fluid and …
human Ureaplasma species are most frequently isolated from the amniotic fluid and …
Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth
JA Keelan - Journal of Reproductive Immunology, 2018 - Elsevier
The central role of inflammatory processes in labour and delivery is now well-recognised.
However, the biomolecular, immunological and endocrine mechanisms involved in the …
However, the biomolecular, immunological and endocrine mechanisms involved in the …