Gut microbiome, liver immunology, and liver diseases
R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …
connected with human physiology. The liver is a central immunological organ that is …
Immunology and immunotherapy of cholangiocarcinoma
Cholangiocarcinoma is the second most common primary liver cancer. Its incidence is low in
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …
AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …
Quantitative microbiome profiling links gut community variation to microbial load
Current sequencing-based analyses of faecal microbiota quantify microbial taxa and
metabolic pathways as fractions of the sample sequence library generated by each …
metabolic pathways as fractions of the sample sequence library generated by each …
Gut microbiome directs hepatocytes to recruit MDSCs and promote cholangiocarcinoma
Gut dysbiosis is commonly observed in patients with cirrhosis and chronic gastrointestinal
disorders; however, its effect on antitumor immunity in the liver is largely unknown. Here we …
disorders; however, its effect on antitumor immunity in the liver is largely unknown. Here we …
[HTML][HTML] Primary sclerosing cholangitis–a comprehensive review
TH Karlsen, T Folseraas, D Thorburn, M Vesterhus - Journal of hepatology, 2017 - Elsevier
Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …
[HTML][HTML] Prognostic factors for advanced colorectal neoplasia in inflammatory bowel disease: systematic review and meta-analysis
AM Wijnands, ME de Jong, MWMD Lutgens… - Gastroenterology, 2021 - Elsevier
Background and Aims Patients with inflammatory bowel disease (IBD) have an increased
risk of colorectal cancer (CRC). We performed a systematic review and meta-analysis to …
risk of colorectal cancer (CRC). We performed a systematic review and meta-analysis to …
Primary sclerosing cholangitis
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …
[HTML][HTML] Optimizing methods and dodging pitfalls in microbiome research
Research on the human microbiome has yielded numerous insights into health and disease,
but also has resulted in a wealth of experimental artifacts. Here, we present suggestions for …
but also has resulted in a wealth of experimental artifacts. Here, we present suggestions for …
Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy
R Tang, Y Wei, Y Li, W Chen, H Chen, Q Wang, F Yang… - Gut, 2018 - gut.bmj.com
Objective A close relationship between gut microbiota and some chronic liver disorders has
recently been described. Herein, we systematically performed a comparative analysis of the …
recently been described. Herein, we systematically performed a comparative analysis of the …