[HTML][HTML] The use of antihypertensive drugs as coadjuvant therapy in cancer

JA Carlos-Escalante, M de Jesus-Sanchez… - Frontiers in …, 2021 - frontiersin.org
Cancer is a complex group of diseases that constitute the second largest cause of mortality
worldwide. The development of new drugs for treating this disease is a long and costly …

[HTML][HTML] Mathematical modeling of antihypertensive therapy

E Kutumova, I Kiselev, R Sharipov, G Lifshits… - Frontiers in …, 2022 - frontiersin.org
Hypertension is a multifactorial disease arising from complex pathophysiological pathways.
Individual characteristics of patients result in different responses to various classes of …

Tolerability of antihypertensive medications in older adults

TS Dharmarajan, L Dharmarajan - Drugs & aging, 2015 - Springer
Several guidelines for hypertension have recently undergone revisions to incorporate an
approach providing choices of medications based on age, race, and specific situations …

[HTML][HTML] Evaluating molecular mechanism of hypotensive peptides interactions with renin and angiotensin converting enzyme

R He, RE Aluko, XR Ju - PloS one, 2014 - journals.plos.org
Our previous study showed that three rapeseed protein-derived peptides (TF, LY and RALP)
inhibited the in vitro activities of angiotensin converting enzyme (ACE) and renin. Oral …

Simultaneous determination of aliskiren hemifumarate, amlodipine besylate, and hydrochlorothiazide in their triple mixture dosage form by capillary zone …

MM Salim, WM Ebeid, N El‐Enany… - Journal of separation …, 2014 - Wiley Online Library
A novel, specific, reliable, and accurate capillary zone electrophoretic method was
developed and validated for the simultaneous determination of aliskiren hemifumarate …

Synchronized separation of seven medications representing most commonly prescribed antihypertensive classes by using reversed‐phase liquid chromatography …

WM Ebeid, EF Elkady, AA El‐Zaher… - Journal of separation …, 2014 - Wiley Online Library
A reversed‐phase high‐performance liquid chromatography method was developed for the
simultaneous determination of the diuretic, hydrochlorothiazide, along with six drugs …

Simultaneous determination of aliskiren hemifumarate, amlodipine besylate and hydrochlorothiazide in spiked human plasma using UPLC-MS/MS

WM Ebeid, EF Elkady, AA El-Zaher… - Journal of …, 2015 - academic.oup.com
Abstract A sensitive UPLC-MS/MS method was developed and validated for simultaneous
estimation of aliskiren hemifumarate (ALS), amlodipine besylate (AML) and …

Ion-Pair LC method for simultaneous determination of aliskiren hemifumarate, amlodipine besylate and hydrochlorothiazide in pharmaceuticals

RI El-Bagary, G Patonay, AA Elzahr, EF Elkady… - Chromatographia, 2014 - Springer
A rapid and precise LC method was developed for the simultaneous determination of
aliskiren hemifumarate (ALS), amlodipine besylate (AML) and hydrochlorothiazide (HCZ) …

Novel renin inhibitors containing derivatives of N‐alkylleucyl‐β‐hydroxy‐γ‐amino acids

I Winiecka, P Jaworski, AP Mazurek… - Journal of Peptide …, 2016 - Wiley Online Library
In search for new drugs lowering arterial blood pressure, which could be applied in anti‐
hypertensive therapy, research concerning agents blocking of renin‐angiotensin‐aldosteron …

Steady‐state and synchronous spectrofluorimetric methods for simultaneous determination of aliskiren hemifumarate and amlodipine besylate in dosage forms

WM Ebeid, EF Elkady, AA El‐Zaher… - …, 2014 - Wiley Online Library
Aliskiren hemifumarate (ALS) and amlodipine besylate (AML) were simultaneously
determined by two different spectrofluorimetric techniques. The first technique depends on …