Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Biocatalysis as key to sustainable industrial chemistry

AR Alcántara, P Domínguez de María… - …, 2022 - Wiley Online Library
The role and power of biocatalysis in sustainable chemistry has been continuously brought
forward step by step to its present outstanding position. The problem‐solving capabilities of …

Broadening the scope of biocatalysis in sustainable organic synthesis

RA Sheldon, D Brady - ChemSusChem, 2019 - Wiley Online Library
This Review is aimed at synthetic organic chemists who may be familiar with organometallic
catalysis but have no experience with biocatalysis, and seeks to provide an answer to the …

Enzymatic late‐stage modifications: better late than never

E Romero, BS Jones, BN Hogg… - Angewandte Chemie …, 2021 - Wiley Online Library
Enzyme catalysis is gaining increasing importance in synthetic chemistry. Nowadays, the
growing number of biocatalysts accessible by means of bioinformatics and enzyme …

Combining a Genetically Engineered Oxidase with Hydrogen‐Bonded Organic Frameworks (HOFs) for Highly Efficient Biocomposites

P Wied, F Carraro, JM Bolivar… - Angewandte Chemie …, 2022 - Wiley Online Library
Enzymes incorporated into hydrogen‐bonded organic frameworks (HOFs) via bottom‐up
synthesis are promising biocomposites for applications in catalysis and sensing. Here, we …

Photo‐biocatalytic cascades: combining chemical and enzymatic transformations fueled by light

FF Özgen, ME Runda, S Schmidt - ChemBioChem, 2021 - Wiley Online Library
In the field of green chemistry, light–an attractive natural agent–has received particular
attention for driving biocatalytic reactions. Moreover, the implementation of light to drive …

Catalytic Aerobic Oxidation of C(sp3)−H Bonds

H Sterckx, B Morel, BUW Maes - … Chemie International Edition, 2019 - Wiley Online Library
Oxidation reactions are a key technology to transform hydrocarbons from petroleum
feedstock into chemicals of a higher oxidation state, allowing further chemical …

Regio‐and stereoselective steroid hydroxylation at C7 by cytochrome P450 monooxygenase mutants

A Li, CG Acevedo‐Rocha, L D'Amore… - Angewandte …, 2020 - Wiley Online Library
Steroidal C7β alcohols and their respective esters have shown significant promise as
neuroprotective and anti‐inflammatory agents to treat chronic neuronal damage like stroke …

Development of continuous flow systems to access secondary amines through previously incompatible biocatalytic cascades

AP Mattey, GJ Ford, J Citoler, C Baldwin… - Angewandte Chemie …, 2021 - Wiley Online Library
A key aim of biocatalysis is to mimic the ability of eukaryotic cells to carry out multistep
cascades in a controlled and selective way. As biocatalytic cascades get more complex …

Synthetic Reagents for Enzyme‐Catalyzed Methylation

X Wen, F Leisinger, V Leopold… - Angewandte …, 2022 - Wiley Online Library
Late‐stage methylation is a key technology in the development of pharmaceutical
compounds. Methyltransferase biocatalysis may provide powerful options to insert methyl …