Immunoglobulin A (IgA) plays a key role in defending mucosal surfaces against attack by
infectious microorganisms. Such sites present a major site of susceptibility due to their vast …

Protein glycosylation has a huge impact on biological processes in all domains of life. The
type of glycan present on a recombinant glycoprotein depends on protein intrinsic features …

Here, we expressed two neutralizing monoclonal antibodies (Abs) against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2; H4 and B38) in three formats: IgG1, IgA1 …

The penetration of substances from the surface to deep inside plant tissues is called
infiltration. Although various plant tissues may be effectively saturated with externally …

In the past three decades, a great interest has arisen in the use of immunoglobulins as
therapeutic agents. In particular, since the approval of the first monoclonal antibody …

Production of biologics in plants, or plant molecular pharming, is a promising protein
expression technology that is receiving increasing attention from the pharmaceutical …

Passive delivery of antibodies to mucosal sites may be a valuable adjunct to COVID-19
vaccination to prevent infection, treat viral carriage, or block transmission. Neutralizing …

N-Glycosylation of immunoglobulin G1 (IgG1) at the heavy chain Fc domain (Asn297) plays
an important role for antibody structure and effector functions. While numerous recombinant …

Control over glycosylation is an important quality parameter in recombinant protein
production. Here, we demonstrate the generation of a marker‐free genome edited Nicotiana …

Main conclusion Genome editing using CRISPR/Cas technology improves the quality of
potato as a food crop and enables its use as both a model plant in fundamental research …