Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Over the last three decades, numerous aptamer-based biosensors have been reported. The
basis of these sensors is the selective binding of target analytes by aptamers. In the last few …

Recent innovations in point-of-care (POC) diagnostic technologies have paved a critical
road for the improved application of biomedicine through the deployment of accurate and …

Peptides represent a promising class of biorecognition elements that can be coupled to
electrochemical transducers. The benefits lie mainly in their stability and selectivity toward a …

Aptamers have become coming-of-age molecular recognition elements in both diagnostic
and therapeutic applications. Generated by SELEX, the 'quality control'of aptamers, which …

The growing use of aptamers as target recognition elements in label-free biosensing
necessitates corresponding transducers that can be used in relevant environments. While …

The widespread use of sulfonamide (SA) antibiotics in animal husbandry has led to residues
of SAs in the environment, causing adverse effects to the ecosystem and a risk of bacterial …

The study of drug–protein interactions can reveal the corresponding binding mechanisms,
providing valuable information for the early phase drug development and development of …

Viral infections are becoming the foremost driver of morbidity, mortality and economic loss
all around the world. Treatment for diseases associated to some deadly viruses are …

Aptamers are nucleic acid bioreceptors that have been used in various applications
including medical diagnostics and as therapeutic agents. Identifying the most optimal …