Past, present, and future of deep brain stimulation: hardware, software, imaging, physiology and novel approaches
Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …
Complications of deep brain stimulation for Parkinson disease and relationship between micro-electrode tracks and hemorrhage: systematic review and meta-analysis
NP Rasiah, R Maheshwary, CS Kwon, JD Bloomstein… - World neurosurgery, 2023 - Elsevier
Background Deep brain stimulation is a common treatment for Parkinson's disease (PD).
Despite strong efficacy in well-selected patients, complications can occur. Intraoperative …
Despite strong efficacy in well-selected patients, complications can occur. Intraoperative …
Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke
Stroke penumbra injury caused by excess glutamate is an important factor in determining
stroke outcome; however, several therapeutic approaches aiming to rescue the penumbra …
stroke outcome; however, several therapeutic approaches aiming to rescue the penumbra …
Interleukin-4 receptor signaling modulates neuronal network activity
N Hanuscheck, C Thalman, M Domingues… - Journal of Experimental …, 2022 - rupress.org
Evidence is emerging that immune responses not only play a part in the central nervous
system (CNS) in diseases but may also be relevant for healthy conditions. We discovered a …
system (CNS) in diseases but may also be relevant for healthy conditions. We discovered a …
Proceedings of the ninth annual deep brain stimulation think tank: advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, pain …
DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based
participants largely in person and overseas participants joining by video conferencing …
participants largely in person and overseas participants joining by video conferencing …
Lead-OR: A multimodal platform for deep brain stimulation surgery
Background: Deep brain stimulation (DBS) electrode implant trajectories are stereotactically
defined using preoperative neuroimaging. To validate the correct trajectory, microelectrode …
defined using preoperative neuroimaging. To validate the correct trajectory, microelectrode …
Multifunctional fibers enable modulation of cortical and deep brain activity during cognitive behavior in macaques
Recording and modulating neural activity in vivo enables investigations of the
neurophysiology underlying behavior and disease. However, there is a dearth of …
neurophysiology underlying behavior and disease. However, there is a dearth of …
Automatic extraction of upper-limb kinematic activity using deep learning-based markerless tracking during deep brain stimulation implantation for Parkinson's disease …
S Baker, A Tekriwal, G Felsen, E Christensen, L Hirt… - Plos one, 2022 - journals.plos.org
Optimal placement of deep brain stimulation (DBS) therapy for treating movement disorders
routinely relies on intraoperative motor testing for target determination. However, in current …
routinely relies on intraoperative motor testing for target determination. However, in current …
Localization of deep brain stimulation trajectories via automatic mapping of microelectrode recordings to MRI
Objective. Suboptimal electrode placement during subthalamic nucleus deep brain
stimulation (STN DBS) surgery may arise from several sources, including frame-based …
stimulation (STN DBS) surgery may arise from several sources, including frame-based …
[HTML][HTML] Wavelet-based bracketing, time–frequency beta burst detection: new insights in Parkinson's disease
Studies have shown that beta band activity is not tonically elevated but comprises
exaggerated phasic bursts of varying durations and magnitudes, for Parkinson's disease …
exaggerated phasic bursts of varying durations and magnitudes, for Parkinson's disease …