Mechanisms and functions of long non-coding RNAs at multiple regulatory levels

X Zhang, W Wang, W Zhu, J Dong, Y Cheng… - International journal of …, 2019 - mdpi.com
Long non-coding (lnc) RNAs are non-coding RNAs longer than 200 nt. lncRNAs primarily
interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression …

FOXO3a in cancer drug resistance

Y Liu, Y Wang, X Li, Y Jia, J Wang, X Ao - Cancer Letters, 2022 - Elsevier
Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

[HTML][HTML] lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment

H Jin, W Du, W Huang, J Yan, Q Tang, Y Chen… - … Therapy-Nucleic Acids, 2021 - cell.com
Breast cancer is a malignant tumor that has a high mortality rate and mostly occurs in
women. Although significant progress has been made in the implementation of personalized …

M2 macrophage-induced lncRNA PCAT6 facilitates tumorigenesis and angiogenesis of triple-negative breast cancer through modulation of VEGFR2

F Dong, S Ruan, J Wang, Y Xia, K Le, X Xiao… - Cell death & …, 2020 - nature.com
As a common female malignancy, triple-negative breast cancer (TNBC) is the most
malignant subtype of breast cancers (BC). This study further studied the role of long …

The network of non-coding RNAs and their molecular targets in breast cancer

F Crudele, N Bianchi, E Reali, M Galasso, C Agnoletto… - Molecular cancer, 2020 - Springer
Abstract Background Non-coding RNAs are now recognized as fundamental components of
the cellular processes. Non-coding RNAs are composed of different classes, including …

[HTML][HTML] Cell cycle related long non-coding RNAs as the critical regulators of breast cancer progression and metastasis

AS Zangouei, M Zangoue, N Taghehchian… - Biological …, 2023 - SciELO Chile
Cell cycle is one of the main cellular mechanisms involved in tumor progression. Almost all
of the active molecular pathways in tumor cells directly or indirectly target the cell cycle …

LncRNA HCG11 promotes proliferation and migration in gastric cancer via targeting miR-1276/CTNNB1 and activating Wnt signaling pathway

H Zhang, H Huang, X Xu, H Wang, J Wang, Z Yao… - Cancer cell …, 2019 - Springer
Background Gastric cancer (GC) is one common cancer which occurs in the stomach
leading to high mortality around the world. Long non-coding RNAs (lncRNAs) were found …

Multidimensional computational study to understand non-coding RNA interactions in breast cancer metastasis

S Chakraborty, S Banerjee - Scientific Reports, 2023 - nature.com
Metastasis is a major breast cancer hallmark due to which tumor cells tend to relocate to
regional or distant organs from their organ of origin. This study is aimed to decipher the …

Identification of expression of CCND1-related lncRNAs in breast cancer

BM Hussen, HJ Hidayat, S Ghafouri-Fard - Pathology-Research and …, 2022 - Elsevier
Cyclin D1 has been shown to participate in the pathogenesis of breast cancer. This cell
cycle-related protein has direct or indirect interactions with long non-coding RNAs …

[HTML][HTML] NAP1L1 promotes proliferation and chemoresistance in glioma by inducing CCND1/CDK4/CDK6 expression through its interaction with HDGF and activation …

Z Chen, Y Xie, H Luo, Y Song, T Que, R Hu… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
The prognosis of glioma is poor as its pathogenesis and mechanisms underlying cisplatin
chemoresistance remain unclear. Nucleosome assembly protein 1 like 1 (NAP1L1) is …