Rho GTPases are well known for their roles in regulating cell migration, and also contribute
to a variety of other cellular responses. They are subdivided into 2 groups: typical and …

Contemporary analyses of cell metabolism have called out three metabolites: ATP, NADH,
and acetyl-CoA, as sentinel molecules whose accumulation represent much of the purpose …

In vitro and in vivo studies and evidence from human tumors have long implicated Rho
GTPase signaling in the formation and dissemination of a range of cancers. Recently next …

Serotonin (5‐HT) induces concentration‐dependent metabolic effects in diverse cell types,
including neurons, entherochromaffin cells, adipocytes, pancreatic beta‐cells, fibroblasts …

The RhoGTPases, with RhoA, Cdc42 and Rac being major members, are a group of key
ubiquitous proteins present in all eukaryotic organisms that subserve such important …

Intracellular pathogens subvert the host cell cytoskeleton to promote their own survival,
replication, and dissemination. Study of these microbes has led to many discoveries about …

Rac1 small GTPase controls essential aspects of cell biology and is a direct target of
numerous bacterial virulence factors. The CNF1 toxin of pathogenic Escherichia coli …

Lysophosphatidic acid (LPA) is a ubiquitously present signalling molecule involved in
diverse cellular processes such as cell migration, proliferation and differentiation. LPA acts …

The cytoskeleton, a dynamic network of cytoplasmic polymers, plays a central role in
numerous fundamental processes, such as development, reproduction, and cellular …

Numerous experimental studies demonstrate that the Ras homolog family of guanosine
triphosphate hydrolases (Rho GTPases) Ras homolog family member A (RhoA), Ras-related …