Amines are present in a large majority of drugs and drug candidates. Consequently, the
asymmetric synthesis of amine containing compounds represents an extremely important …

In this critical review, the ring opening of non-activated 2-substituted aziridinesvia
intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship …

Aziridines are saturated three-membered heterocycles containing one nitrogen atom. These
compounds are among the most fascinating intermediates in organic synthesis, acting as …

Reaction of chiral α-chloro tert-butanesulfinyl aldimines with Grignard reagents efficiently
afforded β-chloro N-sulfinamides in high diastereomeric excess. The latter compounds were …

Reduction of (RS)-N-tert-butanesulfinyl α-halo imines afforded chiral aziridines in good to
excellent yields. Upon reduction of (RS)-N-tert-butanesulfinyl α-halo imines with NaBH4 in …

An efficient and general synthesis of aziridines by the reaction of imines derived from p-
toluenesulfonamides with in situ generated iodomethyllithium, with a simple and rapid …

Cu (OTf) 2 or Zn (OTf) 2 mediated [3+ 2] cycloaddition reactions of various α-alkyl or aryl
substituted N-tosylaziridines with nitriles is described for the syntheses of substituted …

We report a novel, simple, and efficient synthesis of aziridines and 1-chloroalkan-2-amines
by the reaction of imines derived from various aldehydes and p-toluenesulfonamide or …

Reaction of N, N-dibenzyl-O-methylsulfonyl serine methyl ester with a variety of
heteronucleophiles (sodium azide, sodium phthalimide, amines, thiols) and carbanions …

(2‐Cyanoethyl) aziridines and 2‐aryl‐3‐(2‐cyanoethyl) aziridines were deployed as
substrates for an In (OTf) 3‐mediated regio‐and stereoselective ring rearrangement upon …