A meta-analysis comparing the risk of metastases in patients with rectal cancer and MRI-detected extramural vascular invasion (mrEMVI) vs mrEMVI-negative cases

MRS Siddiqui, C Simillis, C Hunter, M Chand… - British journal of …, 2017 - nature.com
Background: Pathological extramural vascular invasion (EMVI) is an independent prognostic
factor in rectal cancer, but can also be identified on MRI-detected extramural vascular …

Risk factors and risk prediction models for colorectal cancer metastasis and recurrence: an umbrella review of systematic reviews and meta-analyses of observational …

W Xu, Y He, Y Wang, X Li, J Young, JPA Ioannidis… - BMC medicine, 2020 - Springer
Background There is a clear need for systematic appraisal of models/factors predicting
colorectal cancer (CRC) metastasis and recurrence because clinical decisions about …

Surgery for colorectal cancer-trends, developments, and future perspectives

M Rentsch, T Schiergens, A Khandoga, J Werner - Visceral medicine, 2016 - karger.com
Background: Although colorectal surgery is long established as the mainstay treatment for
colon cancer, certain topics regarding technical fine-tuning to increase postsurgical …

Different variables predict the outcome of patients with synchronous versus metachronous metastases of colorectal cancer

GA Colloca, A Venturino, D Guarneri - Clinical and Translational Oncology, 2020 - Springer
Purpose Timing of metastasis is a controversial prognostic factor for patients with metastatic
colorectal cancer (mCRC), as well as the performance of the common prognostic variables …

Radiofrequency ablation is beneficial in simultaneous treatment of synchronous liver metastases and primary colorectal cancer

J Hof, HJ Joosten, K Havenga, KP de Jong - PLoS One, 2018 - journals.plos.org
Background In patients with resectable synchronous colorectal liver metastases (CRLM),
either two-staged or simultaneous resections of the primary tumor and liver metastases are …

[HTML][HTML] The Role of Predictive and Prognostic MRI-Based Biomarkers in the Era of Total Neoadjuvant Treatment in Rectal Cancer

S Curcean, A Curcean, D Martin, Z Fekete, A Irimie… - Cancers, 2024 - mdpi.com
Simple Summary Magnetic resonance imaging (MRI) plays a crucial role in rectal cancer
management, offering valuable information for staging, treatment response, and patient …

[HTML][HTML] Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases

HMCS Kumara, H Miyagaki, SA Herath… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND MMP-2 also known as gelatinase A and MMP-7 (matrilysin) are members of
the zinc-dependent family of MMPs (Matrix metalloproteinase). MMP-2 and MMP-7 are …

Colorectal cancer with synchronous unresectable liver metastases: resecting the primary tumor improves survival

N Leone, S Arolfo, R Spadi, MR Fortunato… - International Journal of …, 2023 - Springer
Purpose The optimal treatment strategy of patients affected by colorectal cancer (CRC) with
synchronous unresectable liver metastases (SULM) is at present undefined. It is not known if …

Feasibility of the liver-first approach for patients with initially unresectable and not optimally resectable synchronous colorectal liver metastases

M Okuno, E Hatano, Y Kasai, T Nishio, S Seo, K Taura… - Surgery Today, 2016 - Springer
Purpose To investigate the outcomes of patients with colorectal cancer and initially
unresectable or not optimally resectable liver metastases, who were treated using the liver …

The impact of surgical resection of the primary tumor on the development of synchronous colorectal liver metastasis: a systematic review

H Pinson, S Cosyns, WP Ceelen - Acta Chirurgica Belgica, 2018 - Taylor & Francis
Background: In recent years different therapeutic strategies for synchronously liver
metastasized colorectal cancer were described. Apart from the classical staged surgical …