Objective: To review published evidence on the impact of weight/BMI change on health-
related quality of life (HRQoL) in adults from the US with overweight/obesity. Methods: The …

Background Fatigue is a frequent complaint in patients with inflammatory bowel disease.
Biological drugs have demonstrated beneficial effects on some extraintestinal …

The efficacy of antidepressants in the acute treatment of moderate-to-severe depression
remains a controversial issue. The minimal important difference (MID) is relevant to judge …

Background Major depressive disorder (MDD), a disabling, potentially life-threatening
condition, negatively affects health-related quality of life (HRQoL). This secondary analysis …

Objectives To assess the prevalence, patient–physician communication, treatment and
health outcomes associated with urinary incontinence (UI) among the medically complex …

Psychopharmacological treatment with antidepressants is an essential part of guideline-
based treatment strategies in affective disorders, such as major depressive disorder …

摘要难治性抑郁症是一种常见的, 严重的精神疾病, 与重大疾病负担相关. 大多数患者接受传统抗
抑郁药物治疗后不能获得症状缓解, 因此对临床医生而言仍是精神医学面临的难题之一 …

Background Major depressive disorder (MDD) and postpartum depression (PPD) are
disabling conditions. This integrated analysis of MDD and PPD clinical trials investigated the …

Levomilnacipran, the more active enantiomer of the serotonin and norepinephrine reuptake
inhibitor (SNRI) milnacipran, was recently approved in the US for the treatment of major …

Objective To evaluate the health-related quality of life (HRQoL) burden associated with
postpartum depression (PPD), determine the extent to which clinical response impacts …