Malaria is a major cause of anaemia in tropical areas. Malaria infection causes haemolysis
of infected and uninfected erythrocytes and bone marrow dyserythropoiesis which …

Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

Sexual reproduction is almost universal in eukaryotic life and involves the fusion of male and
female haploid gametes into a diploid cell. The sperm-restricted single-pass transmembrane …

Malaria continues to be one of the world's most devastating infectious tropical diseases, and
alternative strategies to prevent infection and disease spread are urgently needed. These …

Advances in phage therapy and novel applications of phages in biotechnology encourage
interest in phage impact on human and animal immunity. Here we present comparative …

Although global efforts in the past decade have halved the number of deaths due to malaria,
there are still an estimated 219 million cases of malaria a year, causing more than half a …

Introduction Transmission-blocking vaccines (TBV) prevent community spread of malaria by
targeting mosquito sexual stage parasites, a life-cycle bottleneck, and will be used in …

The efficient spread of malaria from infected humans to mosquitoes is a major challenge for
malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to …

A specific humoral response to bacteriophages may follow phage application for medical
purposes, and it may further determine the success or failure of the approach itself. We …

Malaria transmission-blocking vaccines (TBVs) reduce disease transmission by breaking the
continuous cycle of infection between the human host and the mosquito vector. Domain 1 …