Rheumatoid arthritis: extra-articular manifestations and comorbidities

FA Figus, M Piga, I Azzolin, R McConnell… - Autoimmunity reviews, 2021 - Elsevier
Although synovitis is the pathological hallmark of rheumatoid arthritis (RA), many extra-
articular manifestations (EMs) and comorbidities likely occur due to the complex, chronic …

Cardiovascular comorbidity in rheumatic diseases

MT Nurmohamed, M Heslinga, GD Kitas - Nature Reviews …, 2015 - nature.com
Patients with rheumatoid arthritis (RA) and other inflammatory joint diseases (IJDs) have an
increased risk of premature death compared with the general population, mainly because of …

Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE

DPM Symmons, SE Gabriel - Nature Reviews Rheumatology, 2011 - nature.com
The excess risk of cardiovascular disease (CVD) associated with inflammatory rheumatic
diseases has long been recognized. Patients with established rheumatoid arthritis (RA) or …

Cardiovascular disease in rheumatoid arthritis: state of the art and future perspectives

GD Kitas, SE Gabriel - Annals of the rheumatic diseases, 2011 - ard.bmj.com
Rheumatoid arthritis is associated with an increased risk for cardiovascular events, such as
myocardial infarction and stroke. Epidemiological evidence suggests that classic …

Cardiovascular morbidity and mortality in rheumatoid arthritis

SE Gabriel - The American journal of medicine, 2008 - Elsevier
Patients with rheumatoid arthritis (RA) are at increased risk of mortality compared with the
general population. Evidence suggests that this increased mortality can largely be attributed …

The heart and cardiovascular manifestations in rheumatoid arthritis

AE Voskuyl - Rheumatology, 2006 - academic.oup.com
Cardiovascular features in rheumatoid arthritis (RA) are common. Among those are the
classical extra-articular features that not only include pericarditis, cardiomyopathy …

Heart failure risk associated with rheumatoid arthritis–related chronic inflammation

MJ Ahlers, BD Lowery, E Farber‐Eger… - Journal of the …, 2020 - Am Heart Assoc
Background Inflammation may contribute to incident heart failure (HF). Rheumatoid arthritis
(RA), a prototypic inflammatory condition, may serve as a model for understanding …

Autoantibodies and the risk of cardiovascular events

KP Liang, H MARADIT-KREMERS… - The Journal of …, 2009 - jrheum.org
Objective. Inflammation and autoimmunity are associated with increased cardiovascular
(CV) risk in patients with rheumatoid arthritis. This association may also be present in those …

Cardiovascular complications of rheumatoid arthritis: assessment, prevention, and treatment

MJ Kaplan - Rheumatic Disease Clinics, 2010 - rheumatic.theclinics.com
Rheumatoid arthritis (RA), a chronic inflammatory disease that affects approximately 1% of
the general population, is associated with increased mortality and reduced life expectancy …

An evaluation of risk factors for major adverse cardiovascular events during tocilizumab therapy

VU Rao, A Pavlov, M Klearman… - Arthritis & …, 2015 - Wiley Online Library
Objective To evaluate associations between lipid levels, inflammation, and rheumatoid
arthritis (RA) disease activity, at baseline and during treatment, with the risk of major adverse …