The Roles of Fatty Acids and Apolipoproteins in the Kidneys
X Pan - Metabolites, 2022 - mdpi.com
The kidneys are organs that require energy from the metabolism of fatty acids and glucose;
several studies have shown that the kidneys are metabolically active tissues with an …
several studies have shown that the kidneys are metabolically active tissues with an …
Astrocyte-derived clusterin disrupts glial physiology to obstruct remyelination in mouse models of demyelinating diseases
C Chen, Y Shu, C Yan, H Li, Z Huang, SS Shen… - Nature …, 2024 - nature.com
Multiple sclerosis (MS) is a debilitating demyelinating disease characterized by
remyelination failure attributed to inadequate oligodendrocyte precursor cells (OPCs) …
remyelination failure attributed to inadequate oligodendrocyte precursor cells (OPCs) …
Integrated meta-omics reveals the regulatory landscape involved in lipid metabolism between pig breeds
J Sun, F Xie, J Wang, J Luo, T Chen, Q Jiang, Q Xi… - Microbiome, 2024 - Springer
Background Domesticated pigs serve as an ideal animal model for biomedical research and
also provide the majority of meat for human consumption in China. Porcine intramuscular fat …
also provide the majority of meat for human consumption in China. Porcine intramuscular fat …
Glomerular clusterin expression is increased in diabetic nephropathy and protects against oxidative stress-induced apoptosis in podocytes
J He, KL Dijkstra, K Bakker, P Bus, JA Bruijn… - Scientific Reports, 2020 - nature.com
Clusterin, a glycoprotein encoded by the CLU gene, is expressed in many tissues, including
the kidney, and clusterin expression is upregulated in the glomeruli of patients with various …
the kidney, and clusterin expression is upregulated in the glomeruli of patients with various …
Gut Microbiota and Neonatal Acute Kidney Injury
K Yang, H He, W Dong - American Journal of Perinatology, 2024 - thieme-connect.com
Objective To characterize the relationship between gut microbiota and neonatal acute
kidney injury biomarkers based on the gut-kidney axis. Study Design The Pubmed database …
kidney injury biomarkers based on the gut-kidney axis. Study Design The Pubmed database …
Inhibitory regulation of FoxO1 in PPARδ expression drives mitochondria dysfunction and insulin resistance
Forkhead box protein O1 (FoxO1) regulates muscle growth, but the metabolic role of FoxO1
in skeletal muscle and its mechanisms remain unclear. To explore the metabolic role of …
in skeletal muscle and its mechanisms remain unclear. To explore the metabolic role of …
High serum clusterin levels are associated with premature coronary artery disease in a Chinese population
H Zhu, M Liu, T Zhai, H Pan, L Wang… - Diabetes/Metabolism …, 2019 - Wiley Online Library
Background Clusterin plays an important role in the cardiovascular system, and serum
levels of clusterin are higher in coronary artery disease patients. Here, we measured serum …
levels of clusterin are higher in coronary artery disease patients. Here, we measured serum …
[HTML][HTML] Associations between CLU polymorphisms and memory performance: The role of serum lipids in Alzheimer's disease
CLU encoding clusterin, has been reported to associate with Alzherimer's disease (AD) by
genome-wide association studies (GWAS) based on Caucasian populations. Our previous …
genome-wide association studies (GWAS) based on Caucasian populations. Our previous …
[HTML][HTML] Downregulation of fatty acid oxidation led by Hilpda increases G2/M arrest/delay-induced kidney fibrosis
L Liu, T Liu, R Jia, L Zhang, Z Lv, Z He, Y Qu… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Hypoxia-regulated proximal tubular epithelial cells (PTCs) G2/M phase arrest/delay was
involved in production of renal tubulointerstitial fibrosis (TIF). TIF is a common pathological …
involved in production of renal tubulointerstitial fibrosis (TIF). TIF is a common pathological …
Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis
The cochlea contains two extracellular fluids, perilymph and endolymph. Endolymph
exhibits high potential of approximately+ 80−+ 110 mV (depending on species), which …
exhibits high potential of approximately+ 80−+ 110 mV (depending on species), which …