Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance
Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …
most common causes of death worldwide. Since each tumor is unique, there is a need to …
RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
Release mechanisms of major DAMPs
Damage-associated molecular patterns (DAMPs) are endogenous molecules which foment
inflammation and are associated with disorders in sepsis and cancer. Thus, therapeutically …
inflammation and are associated with disorders in sepsis and cancer. Thus, therapeutically …
Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer
H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
[HTML][HTML] The biology, function, and applications of exosomes in cancer
J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …
The role of exosomes and their applications in cancer
Y Zhou, Y Zhang, H Gong, S Luo, Y Cui - International journal of …, 2021 - mdpi.com
Exosomes are very small extracellular vesicles secreted by multiple cell types and are
extensively distributed in various biological fluids. Recent research indicated that exosomes …
extensively distributed in various biological fluids. Recent research indicated that exosomes …
Transcriptome of extracellular vesicles: state-of-the-art
A Turchinovich, O Drapkina, A Tonevitsky - Frontiers in immunology, 2019 - frontiersin.org
Exosomes and microvesicles are two major categories of extracellular vesicles (EVs)
released by almost all cell types and are highly abundant in biological fluids. Both the …
released by almost all cell types and are highly abundant in biological fluids. Both the …
Transfer RNAs: diversity in form and function
As the adaptor that decodes mRNA sequence into protein, the basic aspects of tRNA
structure and function are central to all studies of biology. Yet the complexities of their …
structure and function are central to all studies of biology. Yet the complexities of their …
Diabetic nephropathy: perspective on extracellular vesicles
Y Lu, D Liu, Q Feng, Z Liu - Frontiers in Immunology, 2020 - frontiersin.org
Diabetic nephropathy (DN) is a major microvascular complication of diabetes mellitus. It is
the most frequent cause of end-stage renal disease with no definitive therapy available so …
the most frequent cause of end-stage renal disease with no definitive therapy available so …
Exosomes in sepsis
Sepsis is a severe state of infection with high mortality. Pathogen-associated molecular
patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic …
patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic …