[HTML][HTML] Alzheimer's disease current therapies, novel drug delivery systems and future directions for better disease management
Abstract Alzheimer's disease (AD), is a neurodegenerative disorder that escalates with time,
exerting a significant impact on physical and mental health and leading to death. The …
exerting a significant impact on physical and mental health and leading to death. The …
Three EHDA processes from a detachable spinneret for fabricating drug fast dissolution composites
S Chen, J Zhou, B Fang, Y Ying… - Macromolecular …, 2024 - Wiley Online Library
In this study, three kinds of electrohydrodynamic atomization (EHDA) processes
(electrospraying, electrospinning, and coaxial electrospinning) are implemented to create …
(electrospraying, electrospinning, and coaxial electrospinning) are implemented to create …
Oral empagliflozin-loaded tri-layer core-sheath fibers fabricated using tri-axial electrospinning: enhanced in vitro and in vivo antidiabetic performance
Empagliflozin (EM) was successfully loaded in polycaprolactone/poly (L-lactic
acid)/polymethyl methacrylate (PCL/PLA/PMMA) fibers. In the rat β-cell line (BRIN-BD11) …
acid)/polymethyl methacrylate (PCL/PLA/PMMA) fibers. In the rat β-cell line (BRIN-BD11) …
Design of cinnamaldehyde-and gentamicin-loaded double-layer corneal nanofiber patches with antibiofilm and antimicrobial effects
In this study, two-layer poly (vinyl alcohol)/gelatin (PVA/GEL) nanofiber patches containing
cinnamaldehyde (CA) in the first layer and gentamicin (GEN) in the second layer were …
cinnamaldehyde (CA) in the first layer and gentamicin (GEN) in the second layer were …
The alginate dialdehyde crosslinking on curcumin-loaded zein nanofibers for controllable release
In this study, electrospun zein/alginate dialdehyde (AD) nanofibers were prepared by green
crosslinking. The degree of crosslinking could reach 50.72%, and the diameter of …
crosslinking. The degree of crosslinking could reach 50.72%, and the diameter of …
The role of AMP-activated protein kinase activators on energy balance and cellular metabolism in type 2 diabetes mellitus
Abstract Type 2 Diabetes Mellitus (T2DM) is a growing health concern that leads to
increased morbidity and mortality rates worldwide. A protein complex called AMP-activated …
increased morbidity and mortality rates worldwide. A protein complex called AMP-activated …
A novel high-efficiency transdermal patches for combinational therapy of Alzheimer's disease: Donepezil/vitamin B12-loaded nanofibers
Improving clinical practice in disease-modifying therapies is an important strategy in coping
with the progressive course of Alzheimer's Disease (AD). This study aimed to develop DO …
with the progressive course of Alzheimer's Disease (AD). This study aimed to develop DO …
Connecting in situ cone/jet length in electrospinning to fiber diameter and drug release for the rational design of electrospun drug carriers
N Joy, D Venugopal, AM Gopinath… - Chemical Engineering …, 2024 - Elsevier
Towards enabling the rational design of electrospun drug carriers, this study investigated
relationships between cone/jet features in electrospinning and operating/solution …
relationships between cone/jet features in electrospinning and operating/solution …
Design and in vitro evaluation of curcumin-loaded PLGA nanoparticle-embedded sodium alginate/gelatin 3D printed scaffolds for Alzheimer's disease
HB Yekeler, E Guler, PS Beato, S Priya… - International Journal of …, 2024 - Elsevier
Abstract Background Targeted nanoparticles (NPs) are aimed at improving clinical
outcomes by enhancing the diagnostic and therapeutic efficacy of drugs in the treatment of …
outcomes by enhancing the diagnostic and therapeutic efficacy of drugs in the treatment of …
Sublingual β-Glucan/Vitamin C-loaded nanoparticle-embedded polyethylene oxide nanofibrous mats
Nutritional supplements available in various forms provide the consumer with essential
molecules demanded for well-being retention. Despite the conveniences provided by oral …
molecules demanded for well-being retention. Despite the conveniences provided by oral …