[HTML][HTML] Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue
Recent findings have demonstrated that mitochondria can be transferred between cells to
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …
Autoregulatory control of mitochondrial glutathione homeostasis
Mitochondria must maintain adequate amounts of metabolites for protective and biosynthetic
functions. However, how mitochondria sense the abundance of metabolites and regulate …
functions. However, how mitochondria sense the abundance of metabolites and regulate …
Mechanisms of mitochondrial ROS production in assisted reproduction: the known, the unknown, and the intriguing
JN Cobley - Antioxidants, 2020 - mdpi.com
The consensus that assisted reproduction technologies (ART), like in vitro fertilization, to
induce oxidative stress (ie, the known) belies how oocyte/zygote mitochondria—a major …
induce oxidative stress (ie, the known) belies how oocyte/zygote mitochondria—a major …
A Ca2+-sensor switch for tolerance to elevated salt stress in Arabidopsis
L Steinhorst, G He, LK Moore, S Schültke… - Developmental Cell, 2022 - cell.com
Excessive Na+ in soils inhibits plant growth. Here, we report that Na+ stress triggers primary
calcium signals specifically in a cell group within the root differentiation zone, thus forming a" …
calcium signals specifically in a cell group within the root differentiation zone, thus forming a" …
Exploring the unmapped cysteine redox proteoform landscape
JN Cobley - American Journal of Physiology-Cell …, 2024 - journals.physiology.org
Cysteine redox proteoforms define the diverse molecular states that proteins with cysteine
residues can adopt. A protein with one cysteine residue must adopt one of two binary …
residues can adopt. A protein with one cysteine residue must adopt one of two binary …
Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
K Frudd, T Burgoyne, JR Burgoyne - Nature communications, 2018 - nature.com
Macroautophagy (autophagy) is a crucial cellular stress response for degrading defective
macromolecules and organelles, as well as providing bioenergetic intermediates during …
macromolecules and organelles, as well as providing bioenergetic intermediates during …
Identification of PSD-95 depalmitoylating enzymes
N Yokoi, Y Fukata, A Sekiya, T Murakami… - Journal of …, 2016 - Soc Neuroscience
Postsynaptic density (PSD)-95, the most abundant postsynaptic scaffolding protein, plays a
pivotal role in synapse development and function. Continuous palmitoylation cycles on PSD …
pivotal role in synapse development and function. Continuous palmitoylation cycles on PSD …
Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation
A Percher, S Ramakrishnan, E Thinon… - Proceedings of the …, 2016 - National Acad Sciences
Fatty acylation of cysteine residues provides spatial and temporal control of protein function
in cells and regulates important biological pathways in eukaryotes. Although recent methods …
in cells and regulates important biological pathways in eukaryotes. Although recent methods …
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart
MS Nanadikar, AM Vergel Leon, J Guo… - Nature …, 2023 - nature.com
Redox signaling and cardiac function are tightly linked. However, it is largely unknown
which protein targets are affected by hydrogen peroxide (H2O2) in cardiomyocytes that …
which protein targets are affected by hydrogen peroxide (H2O2) in cardiomyocytes that …
Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation
LA Ligeon, M Pena-Francesch, LD Vanoaica… - Nature …, 2021 - nature.com
Abstract LC3-associated phagocytosis (LAP) contributes to a wide range of cellular
processes and notably to immunity. The stabilization of phagosomes by the …
processes and notably to immunity. The stabilization of phagosomes by the …