Background: Heat Shock Proteins (HSPs) constitute a group of proteins that play a crucial
role in the process of protein folding. HSPs are also known to modulate a number of key …

Hsp70 is a highly conserved and inducible heat shock protein that belongs to the HSP70
family of molecular chaperones and plays a central role in protein homeostasis. The main …

A method of treating a patient who has non-small cell lung carcinoma (NSCLC), lung cancer,
gastric cancer, and/or glioblastoma includes administering to said patient a composition …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
52460698&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

The present invention relates to peptides, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the …

Background The HSP70 family of heat shock protein plays a critical role in protein synthesis
and transport to maintain protein homeostasis. Several studies have indicated that HSP70s …

JAK-STAT3 signaling, while regulating many aspects of cancer development and
progression, promotes invasion and metastasis through activation of key metastasis …

Regional lymph node metastasis negatively affects prognosis in colon cancer patients. The
molecular processes leading to regional lymph node metastasis are only partially …

Dendritic cells (DCs) present exogenous antigens on major histocompatibility complex
(MHC) class I molecules, thereby activating CD8+ T cells, contributing to tumor elimination …

Elevated expression of the inducible heat shock protein 70 (Hsp70) is known to correlate
with poor prognosis in many cancers. Hsp70 confers survival advantage as well as …