[HTML][HTML] Proteomics technologies for cancer liquid biopsies

Z Ding, N Wang, N Ji, ZS Chen - Molecular Cancer, 2022 - Springer
Alterations in DNAs could not reveal what happened in proteins. The accumulated
alterations of DNAs would change the manifestation of proteins. Therefore, as is the case in …

[HTML][HTML] Multifunctional iron oxide magnetic nanoparticles for biomedical applications: A review

HV Tran, NM Ngo, R Medhi, P Srinoi, T Liu… - Materials, 2022 - mdpi.com
Due to their good magnetic properties, excellent biocompatibility, and low price, magnetic
iron oxide nanoparticles (IONPs) are the most commonly used magnetic nanomaterials and …

Functional ligands for improving anticancer drug therapy: current status and applications to drug delivery systems

R Bajracharya, JG Song, BR Patil, SH Lee, HM Noh… - Drug Delivery, 2022 - Taylor & Francis
Conventional chemotherapy lacking target selectivity often leads to severe side effects,
limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both …

[HTML][HTML] Liquid biopsies, novel approaches and future directions

A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Design and synthesis of DNA hydrogel based on EXPAR and CRISPR/Cas14a for ultrasensitive detection of creatine kinase MB

M Chen, J Zhang, Y Peng, J Bai, S Li, D Han… - Biosensors and …, 2022 - Elsevier
Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas systems exhibit
significant potential in developing biosensing technology due to their collateral cleavage …

[HTML][HTML] Fiber-type shifting in sarcopenia of old age: proteomic profiling of the contractile apparatus of skeletal muscles

P Dowling, S Gargan, D Swandulla… - International Journal of …, 2023 - mdpi.com
The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

H Padinharayil, J Varghese, MC John, GK Rajanikant… - Genes & …, 2023 - Elsevier
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …

[HTML][HTML] Biomarkers in neurodegenerative diseases: proteomics spotlight on ALS and Parkinson's disease

R Raghunathan, K Turajane, LC Wong - International Journal of …, 2022 - mdpi.com
Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's
disease (PD) are both characterized by pathogenic protein aggregates that correlate with …

Aptamers: an emerging navigation tool of therapeutic agents for targeted cancer therapy

C Yang, Y Jiang, SH Hao, XY Yan… - Journal of materials …, 2022 - pubs.rsc.org
Chemotherapeutic agents have been used for the treatment of numerous cancers, but due to
poor selectivity and severe systemic side effects, their clinical application is limited. Single …

Clinical applications of plasma proteomics and peptidomics: Towards precision medicine

B He, Z Huang, C Huang… - PROTEOMICS–Clinical …, 2022 - Wiley Online Library
In the context of precision medicine, disease treatment requires individualized strategies
based on the underlying molecular characteristics to overcome therapeutic challenges …