The interleukin-10 family of cytokines and their role in the CNS
AR Burmeister, I Marriott - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Resident cells of the central nervous system (CNS) play an important role in detecting insults
and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune …
and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune …
Neurochemical regulation of the expression and function of glial fibrillary acidic protein in astrocytes
D Li, X Liu, T Liu, H Liu, L Tong, S Jia, YF Wang - Glia, 2020 - Wiley Online Library
Glial fibrillary acidic protein (GFAP), a type III intermediate filament, is a marker of mature
astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs) …
astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs) …
Mechanisms of neuronal dysfunction in HIV-associated neurocognitive disorders
HIV-associated neurocognitive disorder (HAND) is characterized by cognitive and
behavioral deficits in people living with HIV. HAND is still common in patients that take …
behavioral deficits in people living with HIV. HAND is still common in patients that take …
The oral microbiome and inflammation in mild cognitive impairment
I Yang, RA Arthur, L Zhao, J Clark, Y Hu… - Experimental …, 2021 - Elsevier
Inflammation and immune mechanisms are believed to play important roles in Alzheimer's
disease pathogenesis. Research supports the link between poor oral health and Alzheimer's …
disease pathogenesis. Research supports the link between poor oral health and Alzheimer's …
Calcineurin/NFAT signaling in activated astrocytes drives network hyperexcitability in Aβ-bearing mice
P Sompol, JL Furman, MM Pleiss… - Journal of …, 2017 - Soc Neuroscience
Hyperexcitable neuronal networks are mechanistically linked to the pathologic and clinical
features of Alzheimer's disease (AD). Astrocytes are a primary defense against …
features of Alzheimer's disease (AD). Astrocytes are a primary defense against …
The clinical relevance of OSM in inflammatory diseases: a comprehensive review
CL Wolf, C Pruett, D Lighter, CL Jorcyk - Frontiers in Immunology, 2023 - frontiersin.org
Oncostatin M (OSM) is a pleiotropic cytokine involved in a variety of inflammatory responses
such as wound healing, liver regeneration, and bone remodeling. As a member of the …
such as wound healing, liver regeneration, and bone remodeling. As a member of the …
Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases
P Sompol, CM Norris - Frontiers in Aging Neuroscience, 2018 - frontiersin.org
Mounting evidence supports a fundamental role for Ca2+ dysregulation in astrocyte
activation. Though the activated astrocyte phenotype is complex, cell-type targeting …
activation. Though the activated astrocyte phenotype is complex, cell-type targeting …
Astrocytes derived from neural progenitor cells are susceptible to Zika virus infection
EI Rubio-Hernández, M Comas-García… - PLoS …, 2023 - journals.plos.org
Zika virus (ZIKV) was first isolated in 1947. From its isolation until 2007, symptoms of ZIKV-
caused disease were limited (eg, fever, hives, and headache); however, during the epidemic …
caused disease were limited (eg, fever, hives, and headache); however, during the epidemic …
Oncostatin M, an underestimated player in the central nervous system
E Houben, N Hellings, B Broux - Frontiers in immunology, 2019 - frontiersin.org
For a long time, the central nervous system (CNS) was believed to be an immune privileged
organ. In the last decades, it became apparent that the immune system interacts with the …
organ. In the last decades, it became apparent that the immune system interacts with the …
The opening of connexin 43 hemichannels alters hippocampal astrocyte function and neuronal survival in prenatally LPS-exposed adult offspring
CE Chávez, JE Oyarzún, BC Avendaño… - Frontiers in cellular …, 2019 - frontiersin.org
Clinical evidence has revealed that children born from mothers exposed to viral and
bacterial pathogens during pregnancy are more likely to suffer various neurological …
bacterial pathogens during pregnancy are more likely to suffer various neurological …