The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Importance Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder associated
with significant impairment and a lifetime prevalence of 1% to 3%; however, it is often …

Compulsivity is associated with alterations in the structure and the function of parallel and
interacting brain circuits involved in emotional processing (involving both the reward and the …

Like cardiovascular disease and cancer, neurological disorders present an increasing
challenge for an ageing population. Whereas nonpharmacological procedures are routine …

In 1998, we proposed deep brain stimulation as a last-resort treatment option for patients
suffering from severe, treatment-resistant obsessive-compulsive disorder (OCD). Here, 24 …

A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-
refractory obsessive-compulsive disorder (OCD) can be considered an established therapy …

Abstract In 2011 the European Society for the Study of Tourette Syndrome (ESSTS)
published its first European clinical guidelines for the treatment of Tourette Syndrome (TS) …

Deep brain stimulation (DBS) has been proposed for severe, chronic, treatment-refractory
obsessive-compulsive disorder (OCD) patients. Although serious adverse events can occur …

For more than half a century, stereotactic neurosurgical procedures have been available to
treat patients with severe, debilitating symptoms of obsessive-compulsive disorder (OCD) …

Deep brain stimulation (DBS) has emerged as a promising therapy for neuropsychiatric
illnesses, including depression and obsessive-compulsive disorder, but has shown …