Metastasis is the leading cause of cancer-related death and directly associates with cancer
progression, resistance to anticancer therapy, and poor patient survival. Current efforts …

The vast diversity of S100 proteins has demonstrated a multitude of biological correlations
with cell growth, cell differentiation and cell survival in numerous physiological and …

Nonmuscle myosin IIs (NM IIs) are a group of molecular motors involved in a wide variety of
cellular processes including cytokinesis, migration, and control of cell morphology. There …

Non-muscle myosin 2A (NM2A) is a motor cytoskeletal enzyme with crucial importance from
the early stages of development until adulthood. Due to its capacity to convert chemical …

Receptor for advanced glycation end-products (RAGE) is a multiligand binding and single-
pass transmembrane protein taken in diverse chronic inflammatory conditions. RAGE …

Survival of colorectal cancer patients is strongly dependent on development of distant
metastases. S100A4 is a prognostic biomarker and inducer for colorectal cancer metastasis …

Fibroblast to myofibroblast transdifferentiation mediates numerous fibrotic disorders, such as
idiopathic pulmonary fibrosis (IPF). We have previously demonstrated that non-muscle …

Tissue morphogenesis and patterning during development involve the segregation of cell
types. Segregation is driven by differential tissue surface tensions generated by cell types …

Background S100 proteins have been implicated in various aspects of cancer, including
epithelial-mesenchymal transitions (EMT), invasion and metastasis, and also in …

Nonmuscle myosin-II is an actin-based motor that converts chemical energy into force and
movement, and thus functions as a key regulator of the eukaryotic cytoskeleton. Although it …