Do plants contain G protein-coupled receptors?
B Taddese, GJG Upton, GR Bailey, SRD Jordan… - Plant …, 2014 - academic.oup.com
Whether G protein-coupled receptors (GPCR s) exist in plants is a fundamental biological
question. Interest in deorphanizing new GPCR s arises because of their importance in …
question. Interest in deorphanizing new GPCR s arises because of their importance in …
An approach for identifying cytokines based on a novel ensemble classifier
Biology is meaningful and important to identify cytokines and investigate their various
functions and biochemical mechanisms. However, several issues remain, including the …
functions and biochemical mechanisms. However, several issues remain, including the …
Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and genetic algorithm
Z Li, X Zhou, Z Dai, X Zou - BMC bioinformatics, 2010 - Springer
Background Because a priori knowledge about function of G protein-coupled receptors
(GPCRs) can provide useful information to pharmaceutical research, the determination of …
(GPCRs) can provide useful information to pharmaceutical research, the determination of …
Towards improved quality of GPCR models by usage of multiple templates and profile-profile comparison
G-protein coupled receptors (GPCRs) are targets of nearly one third of the drugs at the
current pharmaceutical market. Despite their importance in many cellular processes the …
current pharmaceutical market. Despite their importance in many cellular processes the …
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background G-Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic
cell surface receptors with great pharmacological interest. A broad range of native ligands …
cell surface receptors with great pharmacological interest. A broad range of native ligands …
An improved classification of G-protein-coupled receptors using sequence-derived features
Background G-protein-coupled receptors (GPCRs) play a key role in diverse physiological
processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structures …
processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structures …
[PDF][PDF] Hierarchical classification of G-protein-coupled receptors with a PSO/ACO algorithm
N Holden, AA Freitas - Proceedings of the IEEE Swarm Intelligence …, 2006 - kar.kent.ac.uk
In our previous work we have proposed a hybrid Particle Swarm Optimisation/Ant Colony
Optimisation (PSO/ACO) algorithm for discovering classification rules. In this paper we …
Optimisation (PSO/ACO) algorithm for discovering classification rules. In this paper we …
Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks
Motivation: G-protein coupled receptors are a major class of eukaryotic cell-surface
receptors. A very important aspect of their function is the specific interaction (coupling) with …
receptors. A very important aspect of their function is the specific interaction (coupling) with …
A database for G proteins and their interaction with GPCRs
AL Elefsinioti, PG Bagos, IC Spyropoulos… - BMC …, 2004 - Springer
Background G protein-coupled receptors (GPCRs) transduce signals from extracellular
space into the cell, through their interaction with G proteins, which act as switches forming …
space into the cell, through their interaction with G proteins, which act as switches forming …
Hierarchical classification of protein function with ensembles of rules and particle swarm optimisation
N Holden, AA Freitas - Soft Computing, 2009 - Springer
This paper focuses on hierarchical classification problems where the classes to be predicted
are organized in the form of a tree. The standard top-down divide and conquer approach for …
are organized in the form of a tree. The standard top-down divide and conquer approach for …