[HTML][HTML] Medical plant extracts and natural compounds with a hepatoprotective effect against damage caused by antitubercular drugs: A review

MA Jiménez-Arellanes, GA Gutiérrez-Rebolledo… - Asian Pacific Journal of …, 2016 - Elsevier
Drug-induced liver injury encompasses a spectrum of diseases ranging from mild
biochemical abnormalities to acute liver failure; example of this scenery is hepatotoxicity …

NAT2 variants are associated with drug-induced liver injury caused by anti-tuberculosis drugs in Indonesian patients with tuberculosis

R Yuliwulandari, RW Susilowati… - Journal of human …, 2016 - nature.com
Drug-induced liver injury (DILI) is the most common adverse drug reaction in the treatment of
tuberculosis (TB). Several studies showed that patients with TB and the slow-acetylator …

Glutathione S-transferase M1 and T1 null allele frequencies among Indonesian ethnics toward improved disease risk assessment

K Prayuni, I Razari, R Yuliwulandari - Environmental Toxicology and …, 2019 - Elsevier
Genetic variations in the glutathione S-transferase genes GSTT1 and GSTM1 have been
widely studied, and homozygous deletions or null genotypes have been reported in different …

[PDF][PDF] Hepato-Protective Effect from Natural Compounds, Biological Products and Medicinal Plant Extracts on Antitubercular Drug-Induced Liver Injuries, A Systematic …

OA Ramírez-Marroquín… - Med Aromat Plants (Los …, 2019 - researchgate.net
Tuberculosis is mainly treated with rifampicin, pyrazinamide, isoniazide, ethambutol and/or
streptomycin; however, the first three cause hepato-and nephro-toxicity, then the patient …

Hepatotoxicity Risk Profile of Indonesian Due to Polymorphism of NAT2 and CYP2E1 in Isoniazid Metabolism

SB Santoso, PU Chabibah… - Urecol Journal. Part D …, 2021 - e-journal.urecol.org
This article presents data on drug-induced liver injury events' risk profile due to NAT2 and
CYP2E1 polymorphisms in isoniazid metabolism in Indonesian populations among various …

Pengembangan Metode PCR Multipleks untuk Analisis Genotipe Null Gen GSTM1/GSTT1 pada Pasien Tuberkulosis

K Prayuni, I Razari, S Nihayah… - ARTERI: Jurnal Ilmu …, 2023 - arteri.sinergis.org
Tuberculosis (TB) remains Indonesia's leading infectious disease. Hepatotoxicity is the most
common side effect of TB first-line medication therapy in TB patients. GSTM1 and GSTT1 are …

Status of pharmacogenomics research in India during the last five years

R Priyadarshini, GM Raj, DG Shewade - 2018 - insajournal.in
Studies related to pharmacogenomics have considerably increased in recent years in India.
The interests shown by our researchers are largely reflecting the global trend towards the …

PENGARUH POLIMORFISME ENZIM N-ACETYLTRANSFERASE 2 DAN CYP2E1 TERHADAP ISONIAZID SEBAGAI INDUKTOR HEPATOTOKSIK

PU Chabibah - 2021 - eprintslib.ummgl.ac.id
Pengobatan TB hingga saat ini dipertimbangkan berdasarkan berat badan. Respon klinis
yang berbeda pada setiap pasien bisa disebabkan oleh faktor genetik, banyak penelitian …

[引用][C] Risiko Hepatotoksik Populasi Indonesia Akibat Isoniazid dan Polimorfisme Enzim NAT2 dan CYP2E1

SB Santoso, PU Chabibah, P Pribadi