Microfluidic nanoparticles for drug delivery

Y Liu, G Yang, Y Hui, S Ranaweera, CX Zhao - Small, 2022 - Wiley Online Library
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …

Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Self-assembled polymeric vesicles: Focus on polymersomes in cancer treatment

F Araste, A Aliabadi, K Abnous, SM Taghdisi… - Journal of Controlled …, 2021 - Elsevier
The progress in advanced materials using nanoscale components can be conducted by an
innovative idea involving combining nanotechnology approaches with supramolecular …

Recent Advances in Microfluidic Technologies for the Construction of Artificial Cells

S Tan, Y Ai, X Yin, Z Xue, X Fang… - Advanced Functional …, 2023 - Wiley Online Library
Artificial cells are synthetic constructs that emulate natural cells, with potential applications in
areas of energy science, environmental treatment, and the study of life's origins …

Polymersome Membrane Engineering with Active Targeting or Controlled Permeability for Responsive Drug Delivery

A Kayani, A Raza, J Si, D Dutta, Q Zhou… - Biomacromolecules, 2023 - ACS Publications
Polymersomes have been extensively investigated for drug delivery as nanocarriers for two
decades due to a series of advantages including high stability under physiological …

Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects

A Maged, R Abdelbaset, AA Mahmoud… - Drug delivery, 2022 - Taylor & Francis
Microfluidics is used to manipulate fluid flow in micro-channels to fabricate drug delivery
vesicles in a uniform tunable size. Thanks to their designs, microfluidic technology provides …

pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects

LJC Albuquerque, V Sincari, A Jäger, J Kucka… - Journal of Controlled …, 2021 - Elsevier
The delivery of therapeutics into sites of action by using cargo-delivery platforms potentially
minimizes their premature degradation and fast clearance from the bloodstream …

Mastering the tools: natural versus artificial vesicles in nanomedicine

L Leggio, G Arrabito, V Ferrara… - Advanced …, 2020 - Wiley Online Library
Naturally occurring extracellular vesicles and artificially made vesicles represent important
tools in nanomedicine for the efficient delivery of biomolecules and drugs. Since its first …

Membrane permeability and responsiveness drive performance: linking structural features with the antitumor effectiveness of doxorubicin-loaded stimuli-triggered …

E Jäger, P Černoch, M Vragovic… - …, 2024 - ACS Publications
The permeability and responsiveness of polymer membranes are absolutely relevant in the
design of polymersomes for cargo delivery. Accordingly, we herein correlate the structural …

Polymersomes as the Next Attractive Generation of Drug Delivery Systems: Definition, Synthesis and Applications

M Fonseca, I Jarak, F Victor, C Domingues, F Veiga… - Materials, 2024 - mdpi.com
Polymersomes are artificial nanoparticles formed by the self-assembly process of
amphiphilic block copolymers composed of hydrophobic and hydrophilic blocks. They can …