The cosolvency models frequently used in solubility data modeling of drugs in mixed
solvents were reviewed and their accuracies for calculating the solubility of solutes were …

The cosolvency models presented from 1960 to 2007 were reviewed and their accuracies
for correlating and/or predicting the solubility of drugs in water-cosolvent mixtures were …

The solubility of a solute is an important physico-chemical property of drugs/chemicals and
is highly in demand in the industry. Addition of the second solvent is a common procedure to …

Aqueous solubility is one of the major challenges in the early stages of drug discovery. One
of the most common and effective methods for enhancing solubility is the addition of an …

The available solubility of deferiprone (DFP) in mono and mixed solvent systems is limited.
The aim of this work is to find solvation of DFP with respect to the composition of the solvent …

Two coamorphous drug–amino acid systems, indomethacin–tryptophan (Ind–Trp) and
furosemide–tryptophan (Fur–Trp), were analyzed toward their ease of amorphization and …

Methyl, ethyl and propyl parabens equilibrium solubility was determined in (methanol+
water) binary mixtures at 298.15 K. The mole fraction solubility of these compounds …

In this research, the equilibrium mole fraction solubility of ketoconazole in some aqueous-
ethanolic mixtures was calculated from previously measured solubility data reported in …

This study aimed to provide a rational experimental design to collect a minimum number of
experimental data points for a drug dissolved in a given binary solvent mixture at various …

Here, using in situ atomic force microscopy (AFM), the dissolution behaviors and dissolution
molecular pathways of two azilsartan crystals, the isopropanol solvate (AZ-IPA), and form I …