Synthetic product-based approach toward potential antileishmanial drug development
Leishmaniasis is a parasitic disease and is categorized as a tropically neglected disease
(NTD) with no effective vaccines available. The available chemotherapeutics against …
(NTD) with no effective vaccines available. The available chemotherapeutics against …
Mexican Oregano (Lippia graveolens Kunth) as Source of Bioactive Compounds: A Review
Lippia graveolens is a traditional crop and a rich source of bioactive compounds with
various properties (eg, antioxidant, anti-inflammatory, antifungal, UV defense, anti-glycemic …
various properties (eg, antioxidant, anti-inflammatory, antifungal, UV defense, anti-glycemic …
The role of natural anti-parasitic guided development of synthetic drugs for leishmaniasis
Leishmaniasis is a parasitic disease and categorised as a neglected tropical disease (NTD).
Each year, between 70, 0000 and 1 million new cases are believed to occur. There are …
Each year, between 70, 0000 and 1 million new cases are believed to occur. There are …
The ambiguous role of mannose-binding lectin (MBL) in human immunity
Mannose-binding lectin (MBL) and lectin complement pathway have become targets of
increasing clinical interest. Many aspects of MBL have been recently explored, including the …
increasing clinical interest. Many aspects of MBL have been recently explored, including the …
An appraisal of the scientific current situation and new perspectives in the treatment of cutaneous leishmaniasis
CAB Nieva, AG Cid, AI Romero, MF García-Bustos… - Acta Tropica, 2021 - Elsevier
Abstract Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …
[HTML][HTML] Synthesis, spectroscopic characterization, antileishmanial, DNA binding, antioxidant, cytotoxicity, antifungal and antibacterial studies of organotin (IV) …
S Hussain, S Shujah, A Rehman, ST Hussain… - Arabian Journal of …, 2023 - Elsevier
Six new organotin (IV) complexes,[Bu 2 SnL](1),[Me 2 SnL](2),[Me 3 SnL](3),[Bu 3
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …
Modeling and simulation study to identify threonine synthase as possible drug target in Leishmania major
RJ Meshram, KT Bagul, SU Aouti, AM Shirsath… - Molecular Diversity, 2021 - Springer
Leishmaniasis is one of the most neglected tropical diseases that demand immediate
attention to the identification of new drug targets and effective drug candidates. The present …
attention to the identification of new drug targets and effective drug candidates. The present …
C57BL/6 Peritoneal Macrophage Exosomes Improve Antileishmanial Functions of the RAW264. 7 Cells
H Gandomkar, M Changaei, MM Hosseini… - Parasite …, 2024 - Wiley Online Library
Leishmaniasis is considered one of the most critical health concerns in the world.
Unfortunately, no protective vaccines exist and conventional treatments are relatively …
Unfortunately, no protective vaccines exist and conventional treatments are relatively …
Identification of Novel Antileishmanial Chemotypes By High-Throughput Virtual and In Vitro Screening
Background Leishmaniasis is a deadly protozoan parasitic disease and a significant health
problem in underdeveloped and developing countries. The global spread of the parasite …
problem in underdeveloped and developing countries. The global spread of the parasite …
Annonaceae family alkaloids as agents against Leishmaniasis: a review and molecular docking evaluation
VP Lorenzo, L Scotti… - Current Drug …, 2020 - ingentaconnect.com
Leishmaniasis is a neglected disease that affects 15 million people worldwide. Existing
treatments are associated with limitations, including high costs and toxicity. Several classes …
treatments are associated with limitations, including high costs and toxicity. Several classes …