Association between shortened leukocyte telomere length and cardiometabolic outcomes: systematic review and meta-analysis

MJJ D'Mello, SA Ross, M Briel, SS Anand… - Circulation …, 2015 - Am Heart Assoc
Background—Telomeres are repetitive, gene-poor regions that cap the ends of DNA and
help maintain chromosomal integrity. Their shortening is caused by inflammation and …

Effect of obesity on telomere length: systematic review and meta‐analysis

E Mundstock, EE Sarria, H Zatti, F Mattos Louzada… - …, 2015 - Wiley Online Library
Objective The main objective of this systematic review is to assess the effects of obesity on
telomere length. Methods The following databases were searched: MEDLINE, EMBASE …

Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a …

D Ornish, J Lin, JM Chan, E Epel, C Kemp… - The lancet …, 2013 - thelancet.com
Background Telomere shortness in human beings is a prognostic marker of ageing, disease,
and premature morbidity. We previously found an association between 3 months of …

Telomeres and age-related diseases

HJ Gruber, MD Semeraro, W Renner, M Herrmann - Biomedicines, 2021 - mdpi.com
Telomeres are at the non-coding ends of linear chromosomes. Through a complex 3-
dimensional structure, they protect the coding DNA and ensure appropriate separation of …

Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis

P Willeit, J Raschenberger, EE Heydon, S Tsimikas… - PloS one, 2014 - journals.plos.org
Background Short telomeres have been linked to various age-related diseases. We aimed to
assess the association of telomere length with incident type 2 diabetes mellitus (T2DM) in …

Body mass index and leukocyte telomere length in adults: a systematic review and meta‐analysis

A Müezzinler, AK Zaineddin, H Brenner - Obesity Reviews, 2014 - Wiley Online Library
The objective of this study was to provide a systematic review and meta‐analysis of studies
on the relationship between body mass index (BMI) and leukocyte telomere length (LTL) …

Early life stress and telomere length: investigating the connection and possible mechanisms: a critical survey of the evidence base, research methodology and basic …

I Shalev - Bioessays, 2012 - Wiley Online Library
How can adverse experiences in early life, such as maltreatment, exert such powerful
negative effects on health decades later? The answer may lie in changes to DNA. New …

Effects of physical activity in telomere length: systematic review and meta-analysis

E Mundstock, H Zatti, FM Louzada, SG Oliveira… - Ageing research …, 2015 - Elsevier
The aim of this systematic review is to assess the effects of exercise on telomeres length. We
searched the following databases: MEDLINE, EMBASE, Cochrane Central Register of …

Telomeres and human health

SE Bojesen - Journal of internal medicine, 2013 - Wiley Online Library
Telomeres are the tips of chromosomes and consist of proteins and hexanucleotide tandem
repeats of DNA. The DNA repeats are shortened at each mitotic division of normal cells, and …

Longitudinal association of telomere length and obesity indices in an intervention study with a Mediterranean diet: the PREDIMED-NAVARRA trial

S García-Calzón, A Gea, C Razquin… - International Journal of …, 2014 - nature.com
Background: Telomeres are nucleoprotein structures that protect the ends of eukaryote
chromosomes. Shorter telomere length (TL) is associated with some age-related human …