Endothelial tight junctions and their regulatory signaling pathways in vascular homeostasis and disease

X Cong, W Kong - Cellular signalling, 2020 - Elsevier
Endothelial tight junctions (TJs) regulate the transport of water, ions, and molecules through
the paracellular pathway, serving as an important barrier in blood vessels and maintaining …

[HTML][HTML] Retinal cell damage in diabetic retinopathy

J Zhou, B Chen - Cells, 2023 - mdpi.com
Diabetic retinopathy (DR), the most common microvascular complication that occurs in
diabetes mellitus (DM), is the leading cause of vision loss in working-age adults. The …

Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence

R Simo, C Hernandez - Progress in Retinal and eye Research, 2015 - Elsevier
Diabetic retinopathy remains as a leading cause of blindness in developed countries.
Current treatments target late stages of DR when vision has already been significantly …

[HTML][HTML] The effect of diet and lifestyle on the course of diabetic retinopathy—a review of the literature

A Bryl, M Mrugacz, M Falkowski, K Zorena - Nutrients, 2022 - mdpi.com
Diabetes is a major social problem. As shown by epidemiological studies, the world
incidence of diabetes is increasing and so is the number of people suffering from its …

Animal models of diabetic retinopathy: summary and comparison

AKW Lai, ACY Lo - Journal of diabetes research, 2013 - Wiley Online Library
Diabetic retinopathy (DR) is a microvascular complication associated with chronic exposure
to hyperglycemia and is a major cause of blindness worldwide. Although clinical …

Vitamin D3 Protects against Diabetic Retinopathy by Inhibiting High‐Glucose‐Induced Activation of the ROS/TXNIP/NLRP3 Inflammasome Pathway

L Lu, Q Lu, W Chen, J Li, C Li… - Journal of diabetes …, 2018 - Wiley Online Library
Purpose. This study aimed to evaluate the mechanisms underlying the effects of 1, 25‐
dihydroxyvitamin D (vitamin D3) on diabetes‐induced retinal vascular damage and retinal …

Activation of the TXNIP/NLRP3 inflammasome pathway contributes to inflammation in diabetic retinopathy: a novel inhibitory effect of minocycline

W Chen, M Zhao, S Zhao, Q Lu, L Ni, C Zou, L Lu… - Inflammation …, 2017 - Springer
Objective and design Chronic low-grade inflammation occurs in diabetic retinopathy (DR),
but the underlying mechanism (s) remains (remain) unclear. NLRP3 inflammasome …

[HTML][HTML] Relationships between neurodegeneration and vascular damage in diabetic retinopathy

MG Rossino, M Dal Monte, G Casini - Frontiers in neuroscience, 2019 - frontiersin.org
Diabetic retinopathy (DR) is a common complication of diabetes and constitutes a major
cause of vision impairment and blindness in the world. DR has long been described …

[HTML][HTML] Lycium Barbarum Polysaccharides Reduce Neuronal Damage, Blood-Retinal Barrier Disruption and Oxidative Stress in Retinal Ischemia/Reperfusion Injury

SY Li, D Yang, CM Yeung, WY Yu, RCC Chang, KF So… - PloS one, 2011 - journals.plos.org
Neuronal cell death, glial cell activation, retinal swelling and oxidative injury are
complications in retinal ischemia/reperfusion (I/R) injuries. Lycium barbarum …

Evidence for the effects of yogurt on gut health and obesity

R Pei, DA Martin, DM DiMarco… - Critical reviews in food …, 2017 - Taylor & Francis
Obesity is associated with increased risk for chronic diseases, and affects both developed
and developing nations. Yogurt is a nutrient-dense food that may benefit individuals with …