US7981998B2 - Bis-sulfhydryl macrocyclization systems - Google Patents US7981998B2 -
Bis-sulfhydryl macrocyclization systems - Google Patents Bis-sulfhydryl macrocyclization …

US PATENT DOCUMENTS 4,000,259 A 12/1976 Garsky 4,191,754 A 3, 1980 Veber et al.
5,364,851 A 11/1994 Joran 5,446,128 A 8, 1995 Kahn 5,622,852 A 4/1997 Korsmeyer …

US8889632B2 - Stabilized p53 peptides and uses thereof - Google Patents US8889632B2 -
Stabilized p53 peptides and uses thereof - Google Patents Stabilized p53 peptides and uses …

The present invention provides novel peptidomimetic macro cycles and methods for their
preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and …

The present invention provides biologically active peptido mimetic macrocycles with
improved properties relative to their corresponding polypeptides. The invention additionally …

4,000,259 A 12/1976 Garsky 4,191,754 A 3, 1980 Veber et al. 4,438,270 A 3/1984 Bey et al.
5,364,851 A 11/1994 Joran 5,446,128 A 8, 1995 Kahn 5,622,852 A 4/1997 Korsmeyer …

Provided herein are novel alkynyl and azide containing amino acids; kits containing these
amino acids; peptides containing these amino acids; peptide macrocycles whose secondary …

The present invention provides novel peptidomimetic macro cycles and methods for their
preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and …

(63) Continuation of application No. 12/690,076, filed on 7,723.469 B2 5/2010 Walensky et
al. Jan. 19, 2010, now Pat. No. 8,609,809, which is a 7,786,072 B2 8, 2010 Verdine et al …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
48984724&utm_source= google_patent&utm_medium= platform_link&utm_campaign …