Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones
RH Cote - Pflügers Archiv-European Journal of Physiology, 2021 - Springer
Rod and cone photoreceptors of the vertebrate retina utilize cGMP as the primary
intracellular messenger for the visual signaling pathway that converts a light stimulus into an …
intracellular messenger for the visual signaling pathway that converts a light stimulus into an …
The discovery of the ability of rod photoreceptors to signal single photons
EN Pugh Jr - Journal of General Physiology, 2018 - rupress.org
Vertebrate rod photoreceptors evolved the astonishing ability to respond reliably to single
photons. In parallel, the proximate neurons of the visual system evolved the ability to reliably …
photons. In parallel, the proximate neurons of the visual system evolved the ability to reliably …
Diversity and evolution of frog visual opsins: spectral tuning and adaptation to distinct light environments
Visual systems adapt to different light environments through several avenues including
optical changes to the eye and neurological changes in how light signals are processed and …
optical changes to the eye and neurological changes in how light signals are processed and …
Functional optical coherence tomography enables in vivo optoretinography of photoreceptor dysfunction due to retinal degeneration
Stimulus-evoked intrinsic optical signal (IOS), which occurs almost immediately after the
onset of retinal stimulus has been observed in retinal photoreceptors, promises to be a …
onset of retinal stimulus has been observed in retinal photoreceptors, promises to be a …
[HTML][HTML] Loss of cone function without degeneration in a novel Gnat2 knock-out mouse
Rods and cones mediate visual perception over 9 log units of light intensities, with both
photoreceptor types contributing to a middle 3-log unit range that comprises most night-time …
photoreceptor types contributing to a middle 3-log unit range that comprises most night-time …
Rod photoresponse kinetics limit temporal contrast sensitivity in mesopic vision
Y Umino, Y Guo, CK Chen, R Pasquale… - Journal of …, 2019 - Soc Neuroscience
The mammalian visual system operates over an extended range of ambient light levels by
switching between rod and cone photoreceptors. Rod-driven vision is sluggish, highly …
switching between rod and cone photoreceptors. Rod-driven vision is sluggish, highly …
Transcriptional response to cold and fasting acclimation in Onychostoma macrolepis during the overwintering stage
N Gou, H Ji, W Wu, M Zhong, B Zhang - Comparative Biochemistry and …, 2021 - Elsevier
In this study, we investigated the transcriptome responses of the liver of Onychostoma
macrolepis in by RNA sequencing. The sampling process involved three groups: 1G (0 …
macrolepis in by RNA sequencing. The sampling process involved three groups: 1G (0 …
RBX2 maintains final retinal cell position in a DAB1-dependent and-independent fashion
CL Fairchild, K Hino, JS Han, AM Miltner… - …, 2018 - journals.biologists.com
The laminated structure of the retina is fundamental for the organization of the synaptic
circuitry that translates light input into patterns of action potentials. However, the molecular …
circuitry that translates light input into patterns of action potentials. However, the molecular …
Visual temporal contrast sensitivity in the behaving mouse shares fundamental properties with human psychophysics
Y Umino, R Pasquale, E Solessio - Eneuro, 2018 - eneuro.org
The mammalian visual system has a remarkable capacity to detect differences in contrast
across time, which is known as temporal contrast sensitivity (TCS). Details of the underlying …
across time, which is known as temporal contrast sensitivity (TCS). Details of the underlying …
Temporal contrast sensitivity increases despite photoreceptor degeneration in a mouse model of retinitis pigmentosa
RL Pasquale, Y Guo, Y Umino, B Knox, E Solessio - eneuro, 2021 - eneuro.org
The detection of temporal variations in amplitude of light intensity, or temporal contrast
sensitivity (TCS), depends on the kinetics of rod photoresponse recovery …
sensitivity (TCS), depends on the kinetics of rod photoresponse recovery …