Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …

Cell signalling and endocytic membrane trafficking have traditionally been viewed as distinct
processes. Although our present understanding is incomplete and there are still great …

Clathrin-mediated endocytosis oversees the constitutive packaging of selected membrane
cargoes into transport vesicles that fuse with early endosomes. The process is responsive to …

Albumin has a long historical involvement in design of media for the successful culture of
mammalian cells, in both the research and commercial fields. The potential application of …

Our understanding of endocytosis has evolved remarkably in little more than a decade. This
is the result not only of advances in our knowledge of its molecular and biological workings …

Focal adhesion disassembly is regulated by microtubules (MTs) through an unknown
mechanism that involves dynamin. To test whether endocytosis may be involved, we …

The strength of network biology lies in its ability to derive cell biological information without a
priori mechanistic or molecular knowledge. It is shown here how a careful understanding of …

• Introduction• Membrane ruffling and the formation of the macropinosome• Rabs and
macropinocytosis• The fate of the macropinosome on the endocytic pathway• A role for …

Clathrin-mediated endocytosis (CME) is the major pathway for concentrative uptake of
receptors and receptor–ligand complexes (cargo). Although constitutively internalized …

The heptahelical G protein‐coupled receptor (GPCR) family includes∼ 900 members and is
the largest family of signaling receptors encoded in the mammalian genome. G protein …