Recent progress in the structural modification of chitosan for applications in diversified biomedical fields

H Mittal, SS Ray, BS Kaith, JK Bhatia, J Sharma… - European Polymer …, 2018 - Elsevier
This article critically reviews the recent developments in the structural modifications of
chitosan and its nano-structured variants produced via different techniques and their …

Strategies to improve chitosan hemocompatibility: A review

V Balan, L Verestiuc - European Polymer Journal, 2014 - Elsevier
Due to its remarkable physicochemical and biological properties, chitosan is one of the most
promising polymers for biomedical applications. The cationic nature of chitosan may induce …

Microcarriers in application for cartilage tissue engineering: Recent progress and challenges

SL Ding, X Liu, XY Zhao, KT Wang, W Xiong, ZL Gao… - Bioactive Materials, 2022 - Elsevier
Successful regeneration of cartilage tissue at a clinical scale has been a tremendous
challenge in the past decades. Microcarriers (MCs), usually used for cell and drug delivery …

Preparation and characterization of porous chitosan microspheres and adsorption performance for hexavalent chromium

L Ren, J Xu, Y Zhang, J Zhou, D Chen… - International journal of …, 2019 - Elsevier
Porous chitosan microspheres were successfully developed by the simple procedure of
freezing chitosan hydrogel beads and subsequently lyophilizing the frozen structure in …

Polymer-based porous microcarriers as cell delivery systems for applications in bone and cartilage tissue engineering

Z Zhou, W Wu, J Fang, J Yin - International Materials Reviews, 2021 - Taylor & Francis
For tissue regeneration or repair, a suitable temporary scaffold needs to be constructed for
delivering regenerative cells to damaged or diseased tissue. Scaffold types are currently …

Poly (L-glutamic acid)/chitosan polyelectrolyte complex porous microspheres as cell microcarriers for cartilage regeneration

J Fang, Y Zhang, S Yan, Z Liu, S He, L Cui, J Yin - Acta biomaterialia, 2014 - Elsevier
In this study a novel kind of porous poly (l-glutamic acid)(PLGA)/chitosan polyelectrolyte
complex (PEC) microsphere was developed through electrostatic interaction between PLGA …

Enzymatically crosslinked carboxymethyl–chitosan/gelatin/nano-hydroxyapatite injectable gels for in situ bone tissue engineering application

D Mishra, B Bhunia, I Banerjee, P Datta, S Dhara… - Materials Science and …, 2011 - Elsevier
Present study reports synthesis and characterization of an enzymatically crosslinked
injectable gel (iGel) suitable for cell based bone tissue engineering application. The gel …

In Situ Precipitation of Cluster and Acicular Hydroxyapatite onto Porous Poly(γ-benzyl-l-glutamate) Microcarriers for Bone Tissue Engineering

S Bu, S Yan, R Wang, P Xia, K Zhang… - ACS applied materials …, 2020 - ACS Publications
Bone tissue engineering scaffold based on microcarriers provides an effective approach for
the repair of irregular bone defects. The implantation of microcarriers by injection can reduce …

Nanostructured injectable cell microcarriers for tissue regeneration

Z Zhang, TW Eyster, PX Ma - Nanomedicine, 2016 - Taylor & Francis
Biodegradable polymer microspheres have emerged as cell carriers for the regeneration
and repair of irregularly shaped tissue defects due to their injectability, controllable …

Novel injectable porous poly (γ-benzyl-l-glutamate) microspheres for cartilage tissue engineering: preparation and evaluation

J Fang, Q Yong, K Zhang, W Sun, S Yan… - Journal of Materials …, 2015 - pubs.rsc.org
In search of an injectable cellular delivery vehicle for tissue regeneration, porous
microspheres fabricated from the synthetic polypeptide of poly (γ-benzyl-L …