Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

[HTML][HTML] Exploring the contribution of curcumin to cancer therapy: A systematic review of randomized controlled trials

C De Waure, C Bertola, G Baccarini, M Chiavarini… - Pharmaceutics, 2023 - mdpi.com
Although the anticancer role of curcumin has been extensively addressed in preclinical
research, only a few studies were carried out in humans, with conflicting results. The aim of …

[HTML][HTML] Exploration of the use of natural compounds in combination with chemotherapy drugs for tumor treatment

J Wu, Y Li, Q He, X Yang - Molecules, 2023 - mdpi.com
Currently, chemotherapy is the main treatment for tumors, but there are still problems such
as unsatisfactory chemotherapy results, susceptibility to drug resistance, and serious …

[HTML][HTML] Cancer metabolism as a therapeutic target and review of interventions

MTJ Halma, JA Tuszynski, PE Marik - Nutrients, 2023 - mdpi.com
Cancer is amenable to low-cost treatments, given that it has a significant metabolic
component, which can be affected through diet and lifestyle change at minimal cost. The …

[HTML][HTML] Curcumin and its novel formulations for the treatment of hepatocellular carcinoma: new trends and future perspectives in cancer therapy

SM Meybodi, P Rezaei, N Faraji… - Journal of Functional …, 2023 - Elsevier
Hepatocellular carcinoma (HCC), as a common malignancy of the liver, is the second
leading cause of cancer-related death in the world and mostly occurs in patients with a …

[HTML][HTML] Destroying the shield of cancer stem cells: Natural compounds as promising players in cancer therapy

M Lo Iacono, M Gaggianesi, P Bianca… - Journal of Clinical …, 2022 - mdpi.com
In a scenario where eco-sustainability and a reduction in chemotherapeutic drug waste are
certainly a prerogative to safeguard the biosphere, the use of natural products (NPs) …

Conceptualizing an Integrative Multiple Myeloma Care: The Role of Nutrition, Supplements, and Complementary Modalities

F Andreazzoli, I Levy Yurkovski, E Ben-Arye, M Bonucci - Nutrients, 2024 - mdpi.com
Multiple Myeloma (MM) is the second most prevalent hematologic malignancy, and its
incidence has been increasing enormously in recent years. The prognosis of MM has …

A comprehensive review of the PTEN/PI3K/Akt axis in multiple myeloma: from molecular interactions to potential therapeutic targets

M Alimohammadi, P Rahimzadeh, R Khorrami… - … -Research and Practice, 2024 - Elsevier
Phosphatase and tensin homolog (PTEN), phosphatidylinositol 3-kinase (PI3K), and protein
kinase B (Akt) signaling pathways contribute to the development of several cancers …

Application and potential value of curcumin in prostate cancer: a meta-analysis based on animal models

S Wang, F Zhang, J Chen - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction Curcumin is gaining recognition as an agent for cancer chemoprevention and is
presently administered to humans. However, the limited number of clinical trials conducted …