Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to
autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are …

Collagen is the most widely distributed class of proteins in the human body. The use of
collagen-based biomaterials in the field of tissue engineering applications has been …

Injuries to the peripheral nervous system (PNS) cause neuropathies that lead to weakness
and paralysis, poor or absent sensation, unpleasant and painful neuropathies, and impaired …

Peripheral nerve injury requires optimal conditions in both macro-environment and
microenvironment for promotion of axonal regeneration. However, most repair strategies of …

Peripheral nerve injuries (PNIs) are the most common injury types to affect the nervous
system. Restoration of nerve function after PNI is a challenging medical issue. Extended …

Peripheral nerve injury can lead to great morbidity in those afflicted, ranging from sensory
loss, motor loss, chronic pain, or a combination of deficits. Over time, research has …

Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …

Artificial nerve guide conduits have the advantage over autografts in terms of their
availability and ease of fabrication. However, clinical outcomes associated with the use of …

Traumatic injuries resulting in peripheral nerve lesions often require a graft to bridge the
gap. Although autologous nerve auto-graft is still the first-choice strategy in reconstructions …

Traumatic peripheral nerve injury is a worldwide clinical issue with high morbidity. The
severity of peripheral nerve injury can be classified as neurapraxia, axonotmesis or …