Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …

Tissue engineering is a promising strategy for damaged cartilage tissue repair. Three-
dimensional (3D) printed hydrogel exhibits great potential in cartilage tissue engineering for …

Osteochondral defect repair in osteoarthritis (OA) remains an unsolved clinical problem due
to the lack of enough seed cells in the defect and chronic inflammation in the joint. To …

Damage to cartilage tissues is often difficult to repair owing to chronic inflammation and a
lack of bioactive factors. Therefore, developing bioactive materials, such as hydrogels acting …

The development of biomaterials, stem cells and bioactive factors has led to cartilage tissue
engineering becoming a promising tactic to repair cartilage defects. Various polymer three …

In this study, inspired by the components of cartilage matrix, a photo-cross-linked
extracellular matrix (ECM) bioink composed of modified proteins and polysaccharides was …

Cartilage is a tension-and load-bearing tissue and has a limited capacity for intrinsic self-
healing. While microfracture and arthroplasty are the conventional methods for cartilage …

Osteoarthritis (OA) is a progressive joint disease characterized by inflammation and
cartilage destruction, and its progression is closely related to imbalances in the M1/M2 …

Osteoarthritis (OA) is a chronic degenerative joint disease where the main characteristics
include cartilage degeneration and synovial membrane inflammation. These changes in the …

Background Worldwide, many people suffer from knee injuries and articular cartilage
damage every year, which causes pain and reduces productivity, life quality, and daily …