The proteins of severe acute respiratory syndrome coronavirus-2 (SARS CoV-2 or n-COV19), the cause of COVID-19

FK Yoshimoto - The protein journal, 2020 - Springer
The devastating effects of the recent global pandemic (termed COVID-19 for “coronavirus
disease 2019”) caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV …

COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

SH Nile, A Nile, J Qiu, L Li, X Jia, G Kai - Cytokine & growth factor reviews, 2020 - Elsevier
The outbreak of the novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)
responsible for coronavirus disease 2019 (COVID-19) has developed into an …

First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain

S Iftimie, AF López-Azcona, I Vallverdú… - PloS one, 2021 - journals.plos.org
Many countries have seen a two-wave pattern in reported cases of coronavirus disease-19
during the 2020 pandemic, with a first wave during spring followed by the current second …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies

A Sharma, S Tiwari, MK Deb, JL Marty - International journal of antimicrobial …, 2020 - Elsevier
The emergence and rapid spread of coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a potentially fatal disease …

Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units

LS Shekerdemian, NR Mahmood, KK Wolfe… - JAMA …, 2020 - jamanetwork.com
Importance The recent and ongoing coronavirus disease 2019 (COVID-19) pandemic has
taken an unprecedented toll on adults critically ill with COVID-19 infection. While there is …

Targeting SARS-CoV-2 main protease for treatment of COVID-19: covalent inhibitors structure–activity relationship insights and evolution perspectives

G La Monica, A Bono, A Lauria… - Journal of medicinal …, 2022 - ACS Publications
The viral main protease is one of the most attractive targets among all key enzymes involved
in the SARS-CoV-2 life cycle. Covalent inhibition of the cysteine145 of SARS-CoV-2 MPRO …

Identification of 14 known drugs as inhibitors of the main protease of SARS-CoV-2

MM Ghahremanpour, J Tirado-Rives… - ACS medicinal …, 2020 - ACS Publications
A consensus virtual screening protocol has been applied to ca. 2000 approved drugs to
seek inhibitors of the main protease (Mpro) of SARS-CoV-2, the virus responsible for COVID …

[HTML][HTML] Clinical and pathological investigation of patients with severe COVID-19

S Li, L Jiang, X Li, F Lin, Y Wang, B Li, T Jiang, W An… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
coronavirus 2 (SARS-CoV-2), has become a pandemic. This study addresses the clinical …

A review of potential suggested drugs for coronavirus disease (COVID-19) treatment

P Tarighi, S Eftekhari, M Chizari, M Sabernavaei… - European Journal of …, 2021 - Elsevier
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high
prevalence and easy transmission, which is expanding globally with no conventional …

Clinical update on COVID‐19 in pregnancy: A review article

GA Ryan, NC Purandare, FM McAuliffe… - Journal of Obstetrics …, 2020 - Wiley Online Library
The data pertaining to the COVID‐19 pandemic has been rapidly evolving since the first
confirmed case in December 2019. This review article presents a comprehensive analysis of …