Significance: Among many endogenous mediators, the gasotransmitter hydrogen sulfide
(H2S) plays an important role in the regulation of glucose homeostasis. In this article we …

The treatment of patients with severe coronary and peripheral artery disease represents a
significant clinical need, especially for those patients that require a bypass graft and do not …

Carbon monoxide (CO), a product of heme degradation by heme oxygenases, plays an
important role in vascular homeostasis. Recent evidence indicates that mitochondria are …

Over past few years, there has been a dramatic increase in studying physiological
mechanisms of the activity of various signaling low-molecular molecules that directly or …

Although anxiety is perhaps one of the most significant current medical and social problems,
the neurochemical mechanistic background of this common condition remains to be fully …

Gasotransmitters represent a subfamily of the endogenous gaseous signaling molecules
that include nitric oxide (NO), carbon monoxide (CO), and hydrogen sulphide (H2S). These …

Polycystic ovary syndrome (PCOS), one of the important endocrine disorders affecting
females in the reproductive age, is caused mainly by an abnormal oxidation status that …

Nitric oxide, studied to evaluate its role in cardiovascular physiology, has cardioprotective
and therapeutic effects in cellular signaling, mitochondrial function, and in regulating …

Abstract Hydrogen sulfide (H 2 S), traditionally known for its toxic effects, is now involved in
regulating vascular tone. Here we investigated the vasoconstrictive effect of H 2 S on …

Renal transplantation is the preferred treatment for patients with end-stage renal disease.
The current gold standard of kidney preservation for transplantation is static cold storage …