[HTML][HTML] Evidence regarding vitamin D and risk of COVID-19 and its severity

J Mercola, WB Grant, CL Wagner - Nutrients, 2020 - mdpi.com
Vitamin D deficiency co-exists in patients with COVID-19. At this time, dark skin color,
increased age, the presence of pre-existing illnesses and vitamin D deficiency are features …

[HTML][HTML] Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies

D Tiwari, AR Martineau - Seminars in Immunology, 2023 - Elsevier
Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

The dual role of neutrophils in inflammatory bowel diseases

O Wéra, P Lancellotti, C Oury - Journal of clinical medicine, 2016 - mdpi.com
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
characterised by aberrant immunological responses leading to chronic inflammation without …

Vitamin D: modulator of the immune system

F Baeke, T Takiishi, H Korf, C Gysemans… - Current opinion in …, 2010 - Elsevier
1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3), the active form of vitamin D, is known to
regulate calcium and phosphorus metabolism, thus being a key-player in bone-formation …

Vitamin D3: a helpful immuno‐modulator

M Di Rosa, M Malaguarnera, F Nicoletti… - …, 2011 - Wiley Online Library
The active metabolite of vitamin D, 1α, 25‐dihydroxyvitamin D3 [1, 25 (OH) 2D3], is involved
in calcium and phosphate metabolism and exerts a large number of biological effects …

High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

AR Martineau, PM Timms, GH Bothamley, Y Hanifa… - The Lancet, 2011 - thelancet.com
Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect …

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment

AK Coussens, RJ Wilkinson, Y Hanifa… - Proceedings of the …, 2012 - National Acad Sciences
Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic
antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol …

Vitamin D and respiratory tract infections in childhood

S Esposito, M Lelii - BMC infectious diseases, 2015 - Springer
Abstract Background Respiratory tract infections (RTIs) remain among of the most important
causes of morbidity and mortality among children. Several studies have associated vitamin …

Tuberculosis, pulmonary cavitation, and matrix metalloproteinases

CWM Ong, PT Elkington, JS Friedland - American journal of …, 2014 - atsjournals.org
Tuberculosis (TB), a chronic infectious disease of global importance, is facing the
emergence of drug-resistant strains with few new drugs to treat the infection. Pulmonary …

Host-directed therapeutic strategies for tuberculosis

A Kolloli, S Subbian - Frontiers in medicine, 2017 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of
morbidity and mortality in humans worldwide. Currently, the standard treatment for TB …