The biofilm matrix: multitasking in a shared space
HC Flemming, ED van Hullebusch, TR Neu… - Nature Reviews …, 2023 - nature.com
The biofilm matrix can be considered to be a shared space for the encased microbial cells,
comprising a wide variety of extracellular polymeric substances (EPS), such as …
comprising a wide variety of extracellular polymeric substances (EPS), such as …
The non-attached biofilm aggregate
Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …
following the five-step model of development. Initial biofilm research focused on surface …
[HTML][HTML] Z-form extracellular DNA is a structural component of the bacterial biofilm matrix
Biofilms are community architectures adopted by bacteria inclusive of a self-formed
extracellular matrix that protects resident bacteria from diverse environmental stresses and …
extracellular matrix that protects resident bacteria from diverse environmental stresses and …
Drug delivery strategies for antibiofilm therapy
Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …
biofilms, their widespread clinical use is hindered by poor biocompatibility and …
RNA is a key component of extracellular DNA networks in Pseudomonas aeruginosa biofilms
S Mugunthan, LL Wong, FR Winnerdy… - Nature …, 2023 - nature.com
The extracellular matrix of bacterial biofilms consists of diverse components including
polysaccharides, proteins and DNA. Extracellular RNA (eRNA) can also be present …
polysaccharides, proteins and DNA. Extracellular RNA (eRNA) can also be present …
The structural role of bacterial eDNA in the formation of biofilm streamers
Across diverse habitats, bacteria are mainly found as biofilms, surface-attached communities
embedded in a self-secreted matrix of extracellular polymeric substances (EPS), which …
embedded in a self-secreted matrix of extracellular polymeric substances (EPS), which …
Defeat undefeatable: Ionic liquids as novel antimicrobial agents
J Michalski, C Odrzygóźdź, P Mester, D Narożna… - Journal of Molecular …, 2023 - Elsevier
Emerging antimicrobial resistance and spread of drug-resistant pathogens is currently-one
of the biggest threats posed to global health. Due to that, search of new antimicrobials …
of the biggest threats posed to global health. Due to that, search of new antimicrobials …
Structurally diverse G-quadruplexes as the noncanonical nucleic acid drug target for live cell imaging and antibacterial study
BX Zheng, J Yu, W Long, KH Chan… - Chemical …, 2023 - pubs.rsc.org
The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …
[HTML][HTML] Novel high-throughput screening platform identifies enzymes to tackle biofouling on reverse osmosis membranes
A Møllebjerg, A Zarebska, HB Nielsen, LBS Hansen… - Desalination, 2023 - Elsevier
Biofouling is a ubiquitous problem in many industrial systems including reverse osmosis
(RO) desalination units where the biofilm impedes the water flow. It is essential to develop …
(RO) desalination units where the biofilm impedes the water flow. It is essential to develop …
[HTML][HTML] Interplay between biofilm microenvironment and pathogenicity of Pseudomonas aeruginosa in cystic fibrosis lung chronic infection
O Guillaume, C Butnarasu, S Visentin, E Reimhult - Biofilm, 2022 - Elsevier
Pseudomonas aeruginosa (PA) is a highly, if not the most, versatile microorganism capable
of colonizing diverse environments. One of the niches in which PA is able to thrive is the …
of colonizing diverse environments. One of the niches in which PA is able to thrive is the …