Liposomes hold great potential as gene and drug delivery vehicles due to their
biocompatibility and modular properties, coupled with the major advantage of attenuating …

Gene therapy covers a broad spectrum of applications, from gene replacement and
knockdown for genetic or acquired diseases such as cancer, to vaccination, each with …

Non-viral vectors continue to be an attractive alternative to viral vectors due to their safety,
versatility and ease of preparation and scale-up. Over the past few years, investigators have …

Transient and stable vector transfections have played important roles in illustrating the
function of specific genes/proteins. The general assumption is that such a platform could …

Cationic lipids are positively charged amphiphilic molecules which, for most of them, form
positively charged liposomes, sometimes in combination with a neutral helper lipid. Such …

Complexing TLR9 agonists such as plasmid DNA to cationic liposomes markedly
potentiates their ability to activate innate immunity. We therefore reasoned that liposomes …

Stearic acid (SA) grafted chitosan oligosaccharide (CSO)(CSO–SA), which was synthesized
by an 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-mediated coupling reaction …

Nanoparticles (NPs) have promising applications in medicine. Immune system is an
important protective system to defend organisms from non‐self matters. NPs interact with the …

Gene therapy is a clinical strategy that has the potential to treat an array of genetic and
nongenetic diseases. Vectors for gene transfer are the essential tools of gene therapy. For …

Scavenger receptors act as membrane‐bound and soluble proteins that bind to
macromolecular complexes and pathogens. This diverse supergroup of proteins mediates …