The concept of pellicular particles was imagined by Horváth and Lipsky fifty years ago. They
were initially intended for the analysis of macromolecules. Later, shell particles were …

In this review, we present the latest highlights and trends in the use of core-shell particles as
stationary phases in columns for liquid chromatography (LC). These highly homogeneous …

Using a two-zone moment analysis (TZMA) method based on Brenner's generalized
dispersion theory for two-dimensional (2D) and three-dimensional (3D) periodic media, we …

In the twenty years since its initial demonstration, capillary ultrahigh pressure liquid
chromatography (UHPLC) has proven to be one of most powerful separation techniques for …

We report on a new homogenization approach to solve, with drastically improved speed and
accuracy, the general advection-diffusion equation in hierarchical porous media with …

The two-zone moment-analysis method for the determination of the dispersion tensor in
hierarchical retentive porous media has been adopted to compute and model the effective …

The profile of charge variants represents an important critical quality attribute of protein-
based biopharmaceuticals, in particular of monoclonal antibodies, and must therefore …

The predicted advantages of superficially porous particles over totally porous particles are
decreased eddy dispersion, longitudinal diffusion, and resistance to mass transfer …

The development of new stationary phases has been the key aspect for fast and efficient
high‐performance liquid chromatography separation with relatively low backpressure. Core …

Superficially porous particles are characterized by a non-porous particle core surrounded by
a thin porous layer. Superficially porous particles have been shown to have …