Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

Control of tuberculosis depends on the rapid expression of protective CD4+ T-cell
responses in the Mycobacterium tuberculosis (Mtb)-infected lungs. We have recently shown …

Background Tuberculosis (TB), predominantly caused by Mycobacterium tuberculosis (MTB)
infection, remains a prominent global health challenge. Macrophages are the frontline …

Due to the shortcomings of currently available BCG vaccines, new strategies have been
considered for the development of alternative vaccines against tuberculosis. Many …

Background: For more than a century, the BCG vaccine, derived from an attenuated strain of
Mycobacterium bovis known as bacillus Calmette-Guérin, has been used to prevent …